hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_02263.1
Confidence: Extremely High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| NCF1 | Neutrophil cytosol factor 1 (NCF-1) (47 kDa autosomal chronic granulomatous disease protein) (47 kDa neutrophil oxidase factor) (NCF-47K) (Neutrophil NADPH oxidase factor 1) (Nox organizer 2) (Nox-organizing protein 2) (SH3 and PX domain-containing protein 1A) (p47-phox) | 5 | UniProt NCBI |
| ART3 | Ecto-ADP-ribosyltransferase 3 (EC 2.4.2.31) (ADP-ribosyltransferase C2 and C3 toxin-like 3) (ARTC3) (Mono(ADP-ribosyl)transferase 3) (NAD(P)(+)--arginine ADP-ribosyltransferase 3) | 5 | UniProt NCBI |
| MRE11 | Double-strand break repair protein MRE11 (EC 3.1.-.-) (Double-strand break repair protein MRE11A) (Meiotic recombination 11 homolog 1) (MRE11 homolog 1) (Meiotic recombination 11 homolog A) (MRE11 homolog A) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| KEGG:03450 | 0.0261247873322 | 0.5 | MRE11 | Non-homologous end-joining |
| WP:WP2942 | 0.0435328773163 | 0.5 | MRE11 | DDX1 as a regulatory component of the Drosha microprocessor |
| CORUM:72 | 0.0499419797295 | 0.5 | MRE11 | R/M complex (RAD50-MRE11 complex) |
| CORUM:263 | 0.0499419797295 | 0.5 | MRE11 | R/M complex (RAD50-MRE11 complex) |
| CORUM:264 | 0.0499419797295 | 0.5 | MRE11 | R/M complex (RAD50-MRE11 complex) |
| HP:0100953 | 0.0499436884913 | 0.5 | MRE11 | Enlarged interhemispheric fissure |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| NCF1 | MRE11 | 0.99 | 0.146 | bioplex3_WMM bioplex3_HCT116 WMM_only |
| ART3 | NCF1 | 0.986 | bioplex3_HEK293 bioplex3_WMM WMM_only |
Related Complexes