hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_02270.1
Complex Portal: CPX-22884
Confidence: Extremely High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| TBC1D31 | TBC1 domain family member 31 (WD repeat-containing protein 67) | 5 | UniProt NCBI |
| OFD1 | Centriole and centriolar satellite protein OFD1 (Oral-facial-digital syndrome 1 protein) (Protein 71-7A) | 5 | UniProt NCBI |
| CSPP1 | Centrosome and spindle pole-associated protein 1 | 5 | UniProt NCBI |
| SPICE1 | Spindle and centriole-associated protein 1 (Coiled-coil domain-containing protein 52) (Spindle and centriole-associated protein) | 5 | UniProt NCBI |
| CCDC14 | Coiled-coil domain-containing protein 14 | 5 | UniProt NCBI |
| CCDC138 | Coiled-coil domain-containing protein 138 | 4 | UniProt NCBI |
| SSX2IP | Afadin- and alpha-actinin-binding protein (ADIP) (Afadin DIL domain-interacting protein) (SSX2-interacting protein) | 5 | UniProt NCBI |
| CEP20 | Centrosomal protein 20 (FGFR1OP N-terminal-like protein) (FOP-related protein of 20 kDa) (LisH domain-containing protein FOPNL) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| GO:0034451 | 8.90511742333e-08 | 0.75 | TBC1D31 OFD1 SSX2IP CSPP1 CEP20 CCDC14 | centriolar satellite |
| GO:0005813 | 3.59788777509e-05 | 0.875 | TBC1D31 OFD1 SPICE1 SSX2IP CSPP1 CEP20 CCDC14 | centrosome |
| CORUM:6441 | 7.17483486175e-05 | 0.25 | OFD1 CEP20 | KIAA0753-FOR20-OFD1 complex |
| GO:0005815 | 0.000117690785668 | 0.875 | TBC1D31 OFD1 SPICE1 SSX2IP CSPP1 CEP20 CCDC14 | microtubule organizing center |
| GO:0015630 | 0.00285315545087 | 0.875 | TBC1D31 OFD1 SPICE1 SSX2IP CSPP1 CEP20 CCDC14 | microtubule cytoskeleton |
| GO:0036064 | 0.0147496589733 | 0.5 | CEP20 TBC1D31 OFD1 SSX2IP | ciliary basal body |
| GO:0005856 | 0.0483717117681 | 0.875 | TBC1D31 OFD1 SPICE1 SSX2IP CSPP1 CEP20 CCDC14 | cytoskeleton |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| OFD1 | CEP20 | 0.999 | 0.219565217391 | hein_WMM bioplex3_HEK293 bioplex3_WMM gupta () hein () gupta_WMM | |
| OFD1 | CCDC14 | 0.995 | 0.232 | hein_WMM bioplex3_WMM youn_WMM hein () gupta_WMM gupta () | |
| CCDC14 | SSX2IP | 0.995 | 0.184 | hein_WMM bioplex3_WMM gupta () youn_WMM hein () gupta_WMM | |
| SPICE1 | CCDC14 | 0.993 | 0.27 | hein_WMM bioplex3_WMM youn_WMM gupta_WMM WMM_only | |
| OFD1 | SPICE1 | 0.992 | 0.248 | hein_WMM bioplex3_WMM youn_WMM hein () gupta_WMM gupta () | |
| OFD1 | SSX2IP | 0.99 | 0.204 | hein_WMM bioplex3_WMM gupta () youn_WMM hein () gupta_WMM | |
| CCDC14 | CCDC138 | 0.989 | 0.16 | hein_WMM bioplex3_WMM youn_WMM gupta_WMM WMM_only | |
| CSPP1 | CCDC14 | 0.984 | 0.172 | hein_WMM youn_WMM hein () gupta_WMM | |
| TBC1D31 | OFD1 | 0.983 | 0.108 | hein_WMM youn_WMM hein () gupta_WMM | |
| CCDC14 | CEP20 | 0.98 | 0.172 | hein_WMM hein () gupta_WMM | |
| TBC1D31 | CCDC14 | 0.98 | 0.11 | hein_WMM youn_WMM hein () gupta_WMM | |
| CSPP1 | SPICE1 | 0.976 | 0.18 | hein_WMM youn_WMM gupta_WMM gupta () WMM_only | |
| TBC1D31 | CCDC138 | 0.976 | 0.136 | hein_WMM youn_WMM gupta_WMM WMM_only | |
| OFD1 | CSPP1 | 0.976 | 0.166 | hein_WMM gupta () youn_WMM hein () gupta_WMM | |
| CCDC138 | CEP20 | 0.974 | 0.118 | hein_WMM bioplex3_WMM gupta_WMM WMM_only | |
| SPICE1 | CCDC138 | 0.974 | 0.18 | hein_WMM youn_WMM gupta_WMM gupta () WMM_only | |
| TBC1D31 | SSX2IP | 0.966 | 0.156 | hein_WMM gupta () youn_WMM gupta_WMM | |
| OFD1 | CCDC138 | 0.962 | 0.216 | hein_WMM bioplex3_WMM gupta () youn_WMM hein () gupta_WMM | |
| TBC1D31 | CSPP1 | 0.961 | 0.146 | hein_WMM youn_WMM gupta_WMM WMM_only | |
| TBC1D31 | SPICE1 | 0.959 | 0.13 | hein_WMM youn_WMM gupta_WMM gupta () WMM_only | |
| SPICE1 | SSX2IP | 0.942 | 0.108 | hein_WMM youn_WMM gupta_WMM gupta () WMM_only | |
| SPICE1 | CEP20 | 0.941 | 0.082 | hein_WMM gupta_WMM WMM_only | |
| CSPP1 | SSX2IP | 0.93 | 0.216 | hein_WMM youn_WMM gupta_WMM gupta () WMM_only | |
| CSPP1 | CEP20 | 0.928 | 0.148 | hein_WMM gupta_WMM WMM_only | |
| SSX2IP | CEP20 | 0.928 | 0.108 | hein_WMM gupta_WMM WMM_only | |
| TBC1D31 | CEP20 | 0.928 | 0.088 | hein_WMM gupta_WMM WMM_only | |
| CCDC138 | SSX2IP | 0.911 | 0.15 | hein_WMM gupta () youn_WMM gupta_WMM | |
| CSPP1 | CCDC138 | 0.874 | 0.196 | hein_WMM youn_WMM gupta_WMM WMM_only |
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