hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_02282.1
Complex Portal: CPX-14053
Confidence: Extremely High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| SECTM1 | Secreted and transmembrane protein 1 (Protein K-12) | 5 | UniProt NCBI |
| RAET1E | Retinoic acid early transcript 1E (Lymphocyte effector toxicity activation ligand) (NKG2D ligand 4) (N2DL-4) (NKG2DL4) (RAE-1-like transcript 4) (UL16-binding protein 4) | 5 | UniProt NCBI |
| ADGRA2 | Adhesion G protein-coupled receptor A2 (G-protein coupled receptor 124) (Tumor endothelial marker 5) | 5 | UniProt NCBI |
| ULBP2 | UL16-binding protein 2 (ALCAN-alpha) (NKG2D ligand 2) (N2DL-2) (NKG2DL2) (Retinoic acid early transcript 1H) | 5 | UniProt NCBI |
| ADGRA3 | Adhesion G protein-coupled receptor A3 (G-protein coupled receptor 125) | 5 | UniProt NCBI |
| RYK | Tyrosine-protein kinase RYK (EC 2.7.10.1) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| KEGG:04650 | 0.0419636118509 | 0.333333333333 | ULBP2 RAET1E | Natural killer cell mediated cytotoxicity |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| ADGRA2 | RYK | 0.999 | bioplex3_HEK293 bioplex3_WMM bioplex3_HCT116 WMM_only | ||
| ADGRA3 | RYK | 0.996 | bioplex3_HEK293 bioplex3_WMM bioplex3_HCT116 WMM_only | ||
| SECTM1 | RYK | 0.987 | bioplex3_WMM bioplex3_HCT116 WMM_only | ||
| ULBP2 | RYK | 0.975 | bioplex3_HEK293 bioplex_WMM bioplex3_WMM bioplex3_HCT116 WMM_only | ||
| RAET1E | RYK | 0.955 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | ||
| ADGRA2 | ADGRA3 | 0.941 | bioplex3_WMM WMM_only | ||
| ULBP2 | RAET1E | 0.934 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | ||
| SECTM1 | ADGRA2 | 0.902 | bioplex3_WMM WMM_only | ||
| ULBP2 | ADGRA2 | 0.476 | bioplex3_WMM WMM_only | ||
| SECTM1 | RAET1E | 0.415 | bioplex3_WMM WMM_only | ||
| SECTM1 | ADGRA3 | 0.371 | bioplex3_WMM WMM_only | ||
| SECTM1 | ULBP2 | 0.243 | bioplex3_WMM WMM_only | ||
| ULBP2 | ADGRA3 | 0.223 | 0.098 | bioplex3_WMM WMM_only |
Related Complexes