hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_02328.1
Complex Portal: CPX-11502
Confidence: Extremely High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| MAP3K10 | Mitogen-activated protein kinase kinase kinase 10 (EC 2.7.11.25) (Mixed lineage kinase 2) (Protein kinase MST) | 5 | UniProt NCBI |
| MAP3K9 | Mitogen-activated protein kinase kinase kinase 9 (EC 2.7.11.25) (Mixed lineage kinase 1) | 5 | UniProt NCBI |
| HPCA | Neuron-specific calcium-binding protein hippocalcin (Calcium-binding protein BDR-2) | 5 | UniProt NCBI |
| ANKRD33B | Ankyrin repeat domain-containing protein 33B | 2 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| WP:WP4877 | 0.00110807642161 | 0.5 | MAP3K9 MAP3K10 | Host pathogen interaction of human coronaviruses MAPK signaling |
| WP:WP3915 | 0.0162815495406 | 0.5 | MAP3K9 MAP3K10 | Angiopoietin like protein 8 regulatory pathway |
| WP:WP481 | 0.0255965717397 | 0.5 | MAP3K9 MAP3K10 | Insulin signaling |
| GO:0004706 | 0.042122686785 | 0.5 | MAP3K9 MAP3K10 | JUN kinase kinase kinase activity |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| MAP3K10 | HPCA | 0.999 |
structurally_consistent (dimer)
|
bioplex3_WMM bioplex3_HCT116 WMM_only | |
| MAP3K9 | HPCA | 0.998 |
structurally_consistent (dimer)
|
bioplex3_WMM bioplex3_HCT116 WMM_only | |
| HPCA | ANKRD33B | 0.991 |
structurally_consistent (dimer)
|
bioplex3_WMM bioplex3_HCT116 WMM_only | |
| MAP3K9 | ANKRD33B | 0.902 |
mutually_exclusive (P84074)
|
bioplex3_WMM WMM_only | |
| MAP3K10 | ANKRD33B | 0.902 |
mutually_exclusive (P84074)
|
bioplex3_WMM WMM_only | |
| MAP3K10 | MAP3K9 | 0.902 |
mutually_exclusive (P84074)
|
bioplex3_WMM WMM_only |
Related Complexes