hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_02351.1
Confidence: Extremely High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| XPO4 | Exportin-4 (Exp4) | 5 | UniProt NCBI |
| HOOK2 | Protein Hook homolog 2 (h-hook2) (hHK2) | 5 | UniProt NCBI |
| IPO7 | Importin-7 (Imp7) (Ran-binding protein 7) (RanBP7) | 5 | UniProt NCBI |
| KNTC1 | Kinetochore-associated protein 1 (Rough deal homolog) (HsROD) (Rod) (hRod) | 5 | UniProt NCBI |
| SPN | Leukosialin (GPL115) (Galactoglycoprotein) (GALGP) (Leukocyte sialoglycoprotein) (Sialophorin) (CD antigen CD43) [Cleaved into: CD43 cytoplasmic tail (CD43-ct) (CD43ct)] | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| KEGG:03013 | 0.0125523722118 | 0.5 | XPO4 IPO7 | Nucleocytoplasmic transport |
| WP:WP3302 | 0.049746753544 | 0.25 | XPO4 | eIF5A regulation in response to inhibition of the nuclear export system |
| CORUM:6120 | 0.049938562206 | 0.25 | HOOK2 | Hook2-Vps16 complex |
| CORUM:6121 | 0.049938562206 | 0.25 | HOOK2 | Hook2-Vps41 complex |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| XPO4 | HOOK2 | 0.976 | bioplex_WMM bioplex3_WMM WMM_only | |
| XPO4 | SPN | 0.975 | 0.094 | bioplex3_WMM bioplex3_HCT116 WMM_only |
| XPO4 | KNTC1 | 0.974 | 0.148333333333 | bioplex_WMM bioplex3_WMM WMM_only boldt_WMM |
| XPO4 | IPO7 | 0.953 | 0.156 | bioplex_WMM bioplex3_WMM boldt boldt_WMM WMM_only |
| HOOK2 | IPO7 | 0.884 | bioplex_WMM bioplex3_WMM WMM_only | |
| HOOK2 | KNTC1 | 0.666 | bioplex_WMM bioplex3_WMM WMM_only | |
| IPO7 | KNTC1 | 0.369 | 0.24 | bioplex_WMM bioplex3_WMM youn_WMM WMM_only boldt_WMM |
| IPO7 | SPN | 0.047 | 0.04 | bioplex3_HEK293 bioplex () bioplex3_WMM bioplex3_HCT116 |
Related Complexes