hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_02360.1
Complex Portal: CPX-24131
Confidence: Extremely High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| DMC1 | Meiotic recombination protein DMC1/LIM15 homolog | 5 | UniProt NCBI |
| RAD51 | DNA repair protein RAD51 homolog 1 (HsRAD51) (hRAD51) (RAD51 homolog A) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| WP:WP34 | 0.000185152102942 | 1.0 | DMC1 RAD51 | Ovarian infertility |
| GO:0000150 | 0.000468200720083 | 1.0 | DMC1 RAD51 | DNA strand exchange activity |
| GO:0000730 | 0.00140460216025 | 1.0 | DMC1 RAD51 | DNA recombinase assembly |
| GO:0090735 | 0.00140460216025 | 1.0 | DMC1 RAD51 | DNA repair complex assembly |
| WP:WP5316 | 0.00351405922273 | 1.0 | DMC1 RAD51 | Primary ovarian insufficiency |
| REAC:R-HSA-912446 | 0.00436759503844 | 1.0 | DMC1 RAD51 | Meiotic recombination |
| GO:0042148 | 0.00702301080125 | 1.0 | DMC1 RAD51 | DNA strand invasion |
| GO:0045003 | 0.00702301080125 | 1.0 | DMC1 RAD51 | double-strand break repair via synthesis-dependent strand annealing |
| REAC:R-HSA-1500620 | 0.00828920325958 | 1.0 | DMC1 RAD51 | Meiosis |
| REAC:R-HSA-1474165 | 0.0106216630512 | 1.0 | DMC1 RAD51 | Reproduction |
| CORUM:2824 | 0.0499419797295 | 0.5 | RAD51 | BRCA1-RAD51 complex |
| CORUM:5683 | 0.0499419797295 | 0.5 | RAD51 | hRAD51C-hXRCC3 complex |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| DMC1 | RAD51 | 0.977 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM |
Related Complexes
| Genename | Complexes |
|---|---|
| DMC1 | huMAP3_02360.1 huMAP3_11505.1 huMAP3_13732.1 huMAP3_15298.1 |
| RAD51 | huMAP3_02360.1 huMAP3_13732.1 huMAP3_15298.1 |