hu.MAP 3.0: Complex View

Human Protein Complex Map

Complex: huMAP3_02367.1

Complex Portal: CPX-15709

Confidence: Extremely High

Genename	Protein Name	Uniprot Annotation Score	Links
MRPS26	Small ribosomal subunit protein mS26 (28S ribosomal protein S13, mitochondrial) (MRP-S13) (S13mt) (28S ribosomal protein S26, mitochondrial) (MRP-S26) (S26mt)	4	UniProt NCBI
NOA1	Nitric oxide-associated protein 1	5	UniProt NCBI
ZC3H3	Zinc finger CCCH domain-containing protein 3 (Smad-interacting CPSF-like factor)	5	UniProt NCBI
METTL17	Methyltransferase-like protein 17, mitochondrial (EC 2.1.1.-) (False p73 target gene protein) (Methyltransferase 11 domain-containing protein 1) (Protein RSM22 homolog, mitochondrial)	5	UniProt NCBI
MRPS11	Small ribosomal subunit protein uS11m (28S ribosomal protein S11, mitochondrial) (MRP-S11) (S11mt) (Cervical cancer proto-oncogene 2 protein) (HCC-2)	4	UniProt NCBI
ZNF777	Zinc finger protein 777	5	UniProt NCBI
TRA2A	Transformer-2 protein homolog alpha (TRA-2 alpha) (TRA2-alpha) (Transformer-2 protein homolog A)	5	UniProt NCBI
MRPS12	Small ribosomal subunit protein uS12m (28S ribosomal protein S12, mitochondrial) (MRP-S12) (S12mt) (MT-RPS12)	4	UniProt NCBI
MRPS24	Small ribosomal subunit protein uS3m (28S ribosomal protein S24, mitochondrial) (MRP-S24) (S24mt) (bMRP-47) (bMRP47)	3	UniProt NCBI
MRPL3	Large ribosomal subunit protein uL3m (39S ribosomal protein L3, mitochondrial) (L3mt) (MRP-L3)	4	UniProt NCBI
AURKAIP1	Small ribosomal subunit protein mS38 (28S ribosomal protein S38, mitochondrial) (MRP-S38) (Aurora kinase A-interacting protein) (AURKA-interacting protein)	5	UniProt NCBI
MRPS6	Small ribosomal subunit protein bS6m (28S ribosomal protein S6, mitochondrial) (MRP-S6) (S6mt)	5	UniProt NCBI
MCAT	Malonyl-CoA-acyl carrier protein transacylase, mitochondrial (MCT) (EC 2.3.1.39) (Mitochondrial malonyl CoA:ACP acyltransferase) (Mitochondrial malonyltransferase) ([Acyl-carrier-protein] malonyltransferase)	5	UniProt NCBI

Enrichments

Term ID	Corrected Pval	Fraction Complex Coverage	Proteins	Term Name
REAC:R-HSA-5419276	9.43290325511e-11	0.538461538462	MRPS12 MRPS11 AURKAIP1 MRPS26 MRPL3 MRPS24 MRPS6	Mitochondrial translation termination
REAC:R-HSA-5368286	9.43290325511e-11	0.538461538462	MRPS12 MRPS11 AURKAIP1 MRPS26 MRPL3 MRPS24 MRPS6	Mitochondrial translation initiation
REAC:R-HSA-5389840	9.43290325511e-11	0.538461538462	MRPS12 MRPS11 AURKAIP1 MRPS26 MRPL3 MRPS24 MRPS6	Mitochondrial translation elongation
REAC:R-HSA-5368287	1.52601278109e-10	0.538461538462	MRPS12 MRPS11 AURKAIP1 MRPS26 MRPL3 MRPS24 MRPS6	Mitochondrial translation
CORUM:320	1.77785518933e-09	0.461538461538	MRPS12 MRPS11 MRPS6 MRPS26 MRPL3 MRPS24	55S ribosome, mitochondrial
CORUM:315	1.83450068409e-09	0.384615384615	MRPS26 MRPS12 MRPS6 MRPS24 MRPS11	28S ribosomal subunit, mitochondrial
GO:0000314	5.68920262044e-09	0.461538461538	MRPS12 MRPS11 AURKAIP1 MRPS26 MRPS24 MRPS6	organellar small ribosomal subunit
GO:0005763	5.68920262044e-09	0.461538461538	MRPS12 MRPS11 AURKAIP1 MRPS26 MRPS24 MRPS6	mitochondrial small ribosomal subunit
GO:0000313	1.8747239249e-08	0.538461538462	MRPS12 MRPS11 AURKAIP1 MRPS26 MRPL3 MRPS24 MRPS6	organellar ribosome
GO:0005761	1.8747239249e-08	0.538461538462	MRPS12 MRPS11 AURKAIP1 MRPS26 MRPL3 MRPS24 MRPS6	mitochondrial ribosome
GO:0032543	2.32353514715e-07	0.538461538462	MRPS12 MRPS11 AURKAIP1 MRPS26 MRPL3 MRPS24 MRPS6	mitochondrial translation
GO:0005759	2.73620169494e-07	0.692307692308	MRPS12 MCAT METTL17 MRPS11 AURKAIP1 MRPL3 MRPS26 MRPS24 MRPS6	mitochondrial matrix
REAC:R-HSA-72766	4.54672892303e-07	0.538461538462	MRPS12 MRPS11 AURKAIP1 MRPS26 MRPL3 MRPS24 MRPS6	Translation
GO:0140053	9.7724754575e-07	0.538461538462	MRPS12 MRPS11 AURKAIP1 MRPS26 MRPL3 MRPS24 MRPS6	mitochondrial gene expression
GO:0015935	1.24197683531e-06	0.461538461538	MRPS12 MRPS11 AURKAIP1 MRPS26 MRPS24 MRPS6	small ribosomal subunit
GO:0044391	3.33311295411e-06	0.538461538462	MRPS12 MRPS11 AURKAIP1 MRPS26 MRPL3 MRPS24 MRPS6	ribosomal subunit
GO:0005840	9.12645611478e-06	0.538461538462	MRPS12 MRPS11 AURKAIP1 MRPS26 MRPL3 MRPS24 MRPS6	ribosome
GO:0005743	1.4572519059e-05	0.615384615385	MRPS12 NOA1 MRPS11 AURKAIP1 MRPL3 MRPS26 MRPS24 MRPS6	mitochondrial inner membrane
GO:0019866	2.28961385111e-05	0.615384615385	MRPS12 NOA1 MRPS11 AURKAIP1 MRPL3 MRPS26 MRPS24 MRPS6	organelle inner membrane
GO:0098798	7.73488609076e-05	0.538461538462	MRPS12 MRPS11 AURKAIP1 MRPS26 MRPL3 MRPS24 MRPS6	mitochondrial protein-containing complex
GO:0031966	0.000208404308357	0.615384615385	MRPS12 NOA1 MRPS11 AURKAIP1 MRPL3 MRPS26 MRPS24 MRPS6	mitochondrial membrane
KEGG:03010	0.000229752845331	0.307692307692	MRPL3 MRPS11 MRPS6 MRPS12	Ribosome
GO:0005739	0.000289450402857	0.769230769231	MRPS12 NOA1 METTL17 MRPS11 MCAT AURKAIP1 MRPL3 MRPS26 MRPS24 MRPS6	mitochondrion
GO:0005740	0.00034790669064	0.615384615385	MRPS12 NOA1 MRPS11 AURKAIP1 MRPL3 MRPS26 MRPS24 MRPS6	mitochondrial envelope
GO:1990904	0.000371898449967	0.615384615385	MRPS12 MRPS6 MRPS11 TRA2A MRPL3 MRPS26 MRPS24 AURKAIP1	ribonucleoprotein complex
GO:0003735	0.00523053993714	0.384615384615	MRPL3 MRPS11 MRPS6 MRPS24 MRPS12	structural constituent of ribosome
GO:0006412	0.00607832048563	0.538461538462	MRPS12 MRPS11 AURKAIP1 MRPS26 MRPL3 MRPS24 MRPS6	translation
GO:0043043	0.00743236750508	0.538461538462	MRPS12 MRPS11 AURKAIP1 MRPS26 MRPL3 MRPS24 MRPS6	peptide biosynthetic process
GO:0031967	0.0117901827978	0.615384615385	MRPS12 NOA1 MRPS11 AURKAIP1 MRPL3 MRPS26 MRPS24 MRPS6	organelle envelope
GO:0031975	0.0117901827978	0.615384615385	MRPS12 NOA1 MRPS11 AURKAIP1 MRPL3 MRPS26 MRPS24 MRPS6	envelope
GO:0003723	0.0165832809285	0.692307692308	MRPS12 NOA1 MCAT MRPS11 TRA2A MRPL3 MRPS26 MRPS24 MRPS6	RNA binding
GO:0043604	0.0248417906677	0.538461538462	MRPS12 MRPS11 AURKAIP1 MRPS26 MRPL3 MRPS24 MRPS6	amide biosynthetic process
GO:0006518	0.0272364479095	0.538461538462	MRPS12 MRPS11 AURKAIP1 MRPS26 MRPL3 MRPS24 MRPS6	peptide metabolic process
HPA:0320103	0.0305566096363	0.538461538462	NOA1 MCAT ZNF777 MRPS11 AURKAIP1 MRPS26 MRPS6	nasopharynx; respiratory epithelial cells[High]

Edges

Protein 1	Protein 2	Score	ProteomeHD	Interface Overlap
AURKAIP1	MRPS11	0.998	0.738
TRA2A	MRPS11	0.998	0.08
TRA2A	MRPS6	0.998	0.084
AURKAIP1	MRPS24	0.998	0.622666666667	structurally_consistent (dimer)
MRPL3	MRPS6	0.996	0.826	structurally_consistent (Q5T653)
NOA1	MRPS11	0.996	0.084
MRPS11	MRPS24	0.995	0.462	structurally_consistent (dimer)
MRPS6	MCAT	0.995	0.294	structurally_consistent (dimer)
MRPS24	MRPS6	0.995	0.812	structurally_consistent (P82673) structurally_consistent (dimer)
MRPS26	MRPS11	0.993	0.748	structurally_consistent (dimer)
AURKAIP1	MRPS26	0.993	0.641733990148
METTL17	MRPS6	0.992	0.404
MRPS11	MCAT	0.992	0.174
MRPS26	MRPS6	0.991	0.906	structurally_consistent (dimer)
MRPS26	MRPS24	0.99	0.692
MRPS11	MRPS6	0.988	0.902	structurally_consistent (Q9BYN8)
TRA2A	MRPS24	0.988	0.006	mutually_exclusive (P82673)
AURKAIP1	MRPS6	0.988	0.73
MRPS24	MCAT	0.986	0.178
METTL17	MCAT	0.986	0.308
TRA2A	MRPL3	0.984	0.106
AURKAIP1	METTL17	0.984	0.212
AURKAIP1	NOA1	0.983	0.088
NOA1	MCAT	0.983	0.046
METTL17	MRPS26	0.979	0.42
MRPS26	MCAT	0.979	0.222
NOA1	MRPS6	0.978	0.102
ZNF777	MRPS24	0.975
MRPS26	ZC3H3	0.974	0.166
MRPS26	MRPS12	0.974	0.693903225806
METTL17	MRPS11	0.974	0.3
MRPS26	NOA1	0.972	0.08
MRPS11	MRPS12	0.97	0.49
MRPS12	MRPS6	0.965	0.77
MRPL3	ZC3H3	0.964	0.128
NOA1	MRPS12	0.964	0.116
ZC3H3	MRPS6	0.962	0.158
NOA1	MRPS24	0.959	0.04
AURKAIP1	MRPS12	0.953	0.092
ZNF777	MRPS6	0.953
TRA2A	MRPS26	0.951	0.08
METTL17	MRPS24	0.95	0.264
TRA2A	NOA1	0.948	0.038
ZNF777	MRPS11	0.948
MRPL3	MRPS26	0.929	0.69
AURKAIP1	MCAT	0.926	0.378	structurally_consistent (Q96EY7)
MRPS12	MRPS24	0.923	0.674
MRPL3	MCAT	0.912	0.136
MRPL3	MRPS24	0.866	0.37
MRPS12	MCAT	0.835	0.058
MRPL3	MRPS11	0.831	0.416
METTL17	NOA1	0.814	0.072
TRA2A	ZNF777	0.793
ZNF777	METTL17	0.773
ZNF777	MRPS26	0.761
METTL17	MRPS12	0.741	0.156
ZC3H3	MRPS24	0.721	0.156988372093
ZC3H3	MRPS11	0.718	0.138
TRA2A	ZC3H3	0.7	0.144
MRPL3	AURKAIP1	0.697	0.382
MRPL3	ZNF777	0.651
MRPL3	NOA1	0.437	0.24
ZNF777	MRPS12	0.411
ZNF777	MCAT	0.321
MRPL3	METTL17	0.312	0.536
ZNF777	NOA1	0.308
TRA2A	MCAT	0.227	0.048	mutually_exclusive (P82673)
TRA2A	METTL17	0.18	0.098
MRPL3	MRPS12	0.114	0.688
ZNF777	AURKAIP1	0.082
ZNF777	ZC3H3	0.061
ZC3H3	MRPS12	0.043	0.17
ZC3H3	MCAT	0.035	0.208
TRA2A	MRPS12	0.028	0.068
METTL17	ZC3H3	0.018	0.124
NOA1	ZC3H3	0.015	0.186
TRA2A	AURKAIP1	0.006	0.198

Related Complexes

Genename	Complexes
MRPS26	huMAP3_02367.1 huMAP3_05807.1 huMAP3_05954.1 huMAP3_11899.1
NOA1	huMAP3_02367.1 huMAP3_04115.1 huMAP3_05807.1 huMAP3_05954.1 huMAP3_06043.1
ZC3H3	huMAP3_02367.1 huMAP3_05606.1 huMAP3_05807.1 huMAP3_05935.1
METTL17	huMAP3_01781.1 huMAP3_02367.1 huMAP3_05807.1 huMAP3_05954.1
MRPS11	huMAP3_02367.1 huMAP3_05807.1 huMAP3_05954.1
ZNF777	huMAP3_01382.1 huMAP3_02367.1 huMAP3_05954.1 huMAP3_08215.1 huMAP3_09288.1
TRA2A	huMAP3_00197.1 huMAP3_02367.1 huMAP3_03452.1 huMAP3_04705.1 huMAP3_05807.1 huMAP3_06081.1 huMAP3_06391.1 huMAP3_06589.1 huMAP3_07267.1 huMAP3_07910.1 huMAP3_09587.1 huMAP3_09621.1 huMAP3_10564.1 huMAP3_11073.1
MRPS12	huMAP3_02367.1 huMAP3_04115.1 huMAP3_05807.1 huMAP3_05954.1 huMAP3_06043.1
MRPS24	huMAP3_02367.1 huMAP3_05807.1 huMAP3_05954.1
MRPL3	huMAP3_01022.1 huMAP3_02367.1 huMAP3_04652.1 huMAP3_06439.1 huMAP3_06550.1 huMAP3_06589.1 huMAP3_07939.1 huMAP3_08458.1 huMAP3_09113.1 huMAP3_09483.1 huMAP3_12001.1
AURKAIP1	huMAP3_01781.1 huMAP3_02367.1 huMAP3_05807.1 huMAP3_05954.1 huMAP3_06043.1 huMAP3_07675.1 huMAP3_08562.1 huMAP3_10407.1
MRPS6	huMAP3_02367.1 huMAP3_04652.1 huMAP3_05954.1 huMAP3_06550.1 huMAP3_08458.1 huMAP3_09483.1
MCAT	huMAP3_02367.1 huMAP3_02985.1 huMAP3_05606.1 huMAP3_05807.1 huMAP3_06271.1 huMAP3_07825.1 huMAP3_07939.1 huMAP3_09113.1 huMAP3_09483.1

hu.MAP 3.0: Complex View

Search for a protein

Complex: huMAP3_02367.1

Complex Portal: CPX-15709