hu.MAP 3.0: Complex View

Human Protein Complex Map

Complex: huMAP3_02370.1

Confidence: Extremely High

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Genename	Protein Name	Uniprot Annotation Score	Links
IQGAP1	Ras GTPase-activating-like protein IQGAP1 (p195)	5	UniProt NCBI
IQGAP2	Ras GTPase-activating-like protein IQGAP2	5	UniProt NCBI
MYL12B	Myosin regulatory light chain 12B (MLC-2A) (MLC-2) (Myosin regulatory light chain 2-B, smooth muscle isoform) (Myosin regulatory light chain 20 kDa) (MLC20) (Myosin regulatory light chain MRLC2) (SHUJUN-1)	5	UniProt NCBI
MYL3	Myosin light chain 3 (Cardiac myosin light chain 1) (CMLC1) (Myosin light chain 1, slow-twitch muscle B/ventricular isoform) (MLC1SB) (Ventricular myosin alkali light chain) (Ventricular myosin light chain 1) (VLCl) (Ventricular/slow twitch myosin alkali light chain) (MLC-lV/sb)	5	UniProt NCBI
MYL6	Myosin light polypeptide 6 (17 kDa myosin light chain) (LC17) (Myosin light chain 3) (MLC-3) (Myosin light chain alkali 3) (Myosin light chain A3) (Smooth muscle and nonmuscle myosin light chain alkali 6)	5	UniProt NCBI

Showing 1 to 5 of 5 entries

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Term ID	Corrected Pval	Fraction Complex Coverage	Proteins	Term Name
REAC:R-HSA-195258	0.000131735072349	0.8	IQGAP2 IQGAP1 MYL6 MYL12B	RHO GTPase Effectors
GO:0015629	0.000549054657097	1.0	MYL3 IQGAP1 IQGAP2 MYL6 MYL12B	actin cytoskeleton
KEGG:04814	0.000638513943056	0.6	MYL3 MYL6 MYL12B	Motor proteins
KEGG:04810	0.00111331850639	0.6	IQGAP1 MYL12B IQGAP2	Regulation of actin cytoskeleton
REAC:R-HSA-397014	0.00169462737448	0.6	MYL3 MYL6 MYL12B	Muscle contraction
WP:WP4352	0.00177296321169	0.6	IQGAP1 MYL6 IQGAP2	Ciliary landscape
REAC:R-HSA-416572	0.00259338296865	0.4	MYL6 MYL12B	Sema4D induced cell migration and growth-cone collapse
REAC:R-HSA-5627117	0.00259338296865	0.4	MYL6 MYL12B	RHO GTPases Activate ROCKs
REAC:R-HSA-5625900	0.00259338296865	0.4	MYL6 MYL12B	RHO GTPases activate CIT
REAC:R-HSA-194315	0.00268190833433	0.8	IQGAP2 IQGAP1 MYL6 MYL12B	Signaling by Rho GTPases

Showing 1 to 10 of 29 entries

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Protein 1	Protein 2	Score	ProteomeHD	Evidence
IQGAP2	MYL6	0.995	0.128	bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM boldt youn_WMM bioplex3_HCT116 gupta_WMM fraction boldt_WMM
MYL6	MYL12B	0.993	0.146	hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM boldt youn_WMM hein () bioplex3_HCT116 gupta_WMM boldt_WMM treiber_WMM
MYL3	IQGAP1	0.992	0.174	bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 fraction
MYL6	IQGAP1	0.991	0.252624	hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM boldt youn_WMM hein () bioplex3_HCT116 gupta_WMM fraction boldt_WMM treiber_WMM
MYL12B	IQGAP1	0.984	0.544	hein_WMM bioplex3_HEK293 bioplex_WMM bioplex3_WMM boldt youn_WMM bioplex3_HCT116 gupta_WMM boldt_WMM WMM_only
MYL6	MYL3	0.975	0.09	bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116
MYL12B	MYL3	0.869	0.676	bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116
IQGAP2	MYL12B	0.806	0.124	bioplex3_HEK293 bioplex_WMM bioplex3_WMM youn_WMM bioplex3_HCT116 gupta_WMM boldt_WMM WMM_only
IQGAP2	IQGAP1	0.503	0.262	bioplex_WMM bioplex3_WMM boldt youn_WMM gupta_WMM boldt_WMM treiber_WMM WMM_only
IQGAP2	MYL3	0.008	0.106	bioplex3_HEK293 bioplex ()

Showing 1 to 10 of 10 entries

Related Complexes

Genename	Complexes
MYL6	huMAP3_02370.1 huMAP3_03169.1 huMAP3_05350.1 huMAP3_05543.1 huMAP3_06098.1 huMAP3_06531.1 huMAP3_07968.1 huMAP3_08039.1 huMAP3_09441.1 huMAP3_10270.1
MYL12B	huMAP3_02370.1 huMAP3_06098.1 huMAP3_06531.1 huMAP3_08039.1 huMAP3_09542.1 huMAP3_10270.1
MYL3	huMAP3_02370.1 huMAP3_03169.1 huMAP3_05350.1 huMAP3_05543.1 huMAP3_06098.1 huMAP3_06531.1 huMAP3_08039.1 huMAP3_09789.1 huMAP3_10270.1 huMAP3_15295.1
IQGAP2	huMAP3_00809.1 huMAP3_02370.1 huMAP3_02834.1 huMAP3_05543.1 huMAP3_06531.1 huMAP3_08039.1 huMAP3_08200.1 huMAP3_09441.1 huMAP3_10270.1 huMAP3_10273.1 huMAP3_10665.1 huMAP3_12336.1 huMAP3_13036.1
IQGAP1	huMAP3_02370.1 huMAP3_05543.1 huMAP3_06098.1 huMAP3_06445.1 huMAP3_06531.1 huMAP3_08039.1 huMAP3_10270.1