List of Gene Names or Uniprot ACCs (ex. OFD1 PCM1 Q1MSJ5):

Enrichment (ex. cilium):

Protein (ex. Centrosomal protein):

Complex: huMAP3_02374.1

Confidence: Extremely High   ?

Proteins

Genename	Protein Name	Uniprot Annotation Score	Links
GLOD4	Glyoxalase domain-containing protein 4	4	UniProt   NCBI
ERBB3	Receptor tyrosine-protein kinase erbB-3 (EC 2.7.10.1) (Proto-oncogene-like protein c-ErbB-3) (Tyrosine kinase-type cell surface receptor HER3)	5	UniProt   NCBI
NRG1	Pro-neuregulin-1, membrane-bound isoform (Pro-NRG1) [Cleaved into: Neuregulin-1 (Acetylcholine receptor-inducing activity) (ARIA) (Breast cancer cell differentiation factor p45) (Glial growth factor) (Heregulin) (HRG) (Neu differentiation factor) (Sensory and motor neuron-derived factor)]	5	UniProt   NCBI



Enrichments

Term ID	Corrected Pval	Fraction Complex Coverage	Proteins	Term Name
WP:WP2864	0.00106952227093	0.666666666667	ERBB3 NRG1	Apoptosis related network due to altered Notch3 in ovarian cancer
KEGG:01521	0.00205509166508	0.666666666667	ERBB3 NRG1	EGFR tyrosine kinase inhibitor resistance
KEGG:04012	0.00216826178203	0.666666666667	ERBB3 NRG1	ErbB signaling pathway
WP:WP4806	0.00347772346958	0.666666666667	ERBB3 NRG1	EGFR tyrosine kinase inhibitor resistance
WP:WP673	0.00365686215758	0.666666666667	ERBB3 NRG1	ErbB signaling pathway
GO:0043125	0.0140440992017	0.666666666667	ERBB3 NRG1	ErbB-3 class receptor binding
CORUM:5441	0.0499402709677	0.333333333333	NRG1	NRG1-IKZF4 complex
CORUM:6505	0.0499402709677	0.333333333333	ERBB3	ERBB3-SPG1 complex



Edges

Protein 1	Protein 2	Score ?	ProteomeHD?	Evidence ?
ERBB3	NRG1	0.996		bioplex3_WMM     bioplex3_HCT116     WMM_only
GLOD4	NRG1	0.978		bioplex3_WMM     bioplex3_HCT116     WMM_only
GLOD4	ERBB3	0.005		bioplex3_HCT116     WMM_only





Related Complexes

Genename	Complexes
GLOD4	huMAP3_02374.1 huMAP3_03276.1 huMAP3_13697.1 huMAP3_14870.1
ERBB3	huMAP3_02374.1 huMAP3_03276.1 huMAP3_11283.1 huMAP3_14574.1
NRG1	huMAP3_02374.1 huMAP3_03276.1 huMAP3_07557.1