hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_02427.1
Confidence: Extremely High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| SFTPA2 | Pulmonary surfactant-associated protein A2 (PSP-A) (PSPA) (SP-A) (SP-A2) (35 kDa pulmonary surfactant-associated protein) (Alveolar proteinosis protein) (Collectin-5) | 5 | UniProt NCBI |
| NKIRAS1 | NF-kappa-B inhibitor-interacting Ras-like protein 1 (I-kappa-B-interacting Ras-like protein 1) (Kappa B-Ras protein 1) (KappaB-Ras1) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-181438 | 0.00795599471791 | 1.0 | SFTPA2 NKIRAS1 | Toll Like Receptor 2 (TLR2) Cascade |
| REAC:R-HSA-168179 | 0.00795599471791 | 1.0 | SFTPA2 NKIRAS1 | Toll Like Receptor TLR1:TLR2 Cascade |
| REAC:R-HSA-166016 | 0.0128208394262 | 1.0 | SFTPA2 NKIRAS1 | Toll Like Receptor 4 (TLR4) Cascade |
| REAC:R-HSA-168898 | 0.0171064139006 | 1.0 | SFTPA2 NKIRAS1 | Toll-like Receptor Cascades |
| REAC:R-HSA-5687868 | 0.0249718442457 | 0.5 | SFTPA2 | Defective SFTPA2 causes IPF |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| SFTPA2 | NKIRAS1 | 0.998 | bioplex3_WMM bioplex3_HCT116 WMM_only |
Related Complexes
| Genename | Complexes |
|---|---|
| SFTPA2 | huMAP3_00635.1 huMAP3_02427.1 huMAP3_03033.1 huMAP3_12561.1 |
| NKIRAS1 | huMAP3_01747.1 huMAP3_02427.1 huMAP3_03033.1 huMAP3_07258.1 huMAP3_09939.1 huMAP3_11647.1 huMAP3_12882.1 huMAP3_14434.1 huMAP3_15179.1 |