hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_02439.1
Confidence: Extremely High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| MRPS18A | Large ribosomal subunit protein mL66 (39S ribosomal protein S18-3, mitochondrial) (MRP-S18-3) (39S ribosomal protein S18a, mitochondrial) (MRP-S18-a) (Mrps18a) (S18mt-a) (Large ribosomal subunit protein bS18a) | 4 | UniProt NCBI |
| MRPL39 | Large ribosomal subunit protein mL39 (39S ribosomal protein L39, mitochondrial) (L39mt) (MRP-L39) (39S ribosomal protein L5, mitochondrial) (L5mt) (MRP-L5) | 5 | UniProt NCBI |
| MRPL48 | Large ribosomal subunit protein mL48 (39S ribosomal protein L48, mitochondrial) (L48mt) (MRP-L48) | 4 | UniProt NCBI |
| MRPL44 | Large ribosomal subunit protein mL44 (EC 3.1.26.-) (39S ribosomal protein L44, mitochondrial) (L44mt) (MRP-L44) | 5 | UniProt NCBI |
| MRPL47 | Large ribosomal subunit protein uL29m (39S ribosomal protein L47, mitochondrial) (L47mt) (MRP-L47) (Nasopharyngeal carcinoma metastasis-related protein 1) | 4 | UniProt NCBI |
| MRPL38 | Large ribosomal subunit protein mL38 (39S ribosomal protein L38, mitochondrial) (L38mt) (MRP-L38) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:320 | 2.31097803998e-12 | 1.0 | MRPL38 MRPL39 MRPL48 MRPL44 MRPS18A MRPL47 | 55S ribosome, mitochondrial |
| REAC:R-HSA-5419276 | 6.86533657464e-12 | 1.0 | MRPL38 MRPL39 MRPL48 MRPL44 MRPS18A MRPL47 | Mitochondrial translation termination |
| REAC:R-HSA-5368286 | 6.86533657464e-12 | 1.0 | MRPL38 MRPL39 MRPL48 MRPL44 MRPS18A MRPL47 | Mitochondrial translation initiation |
| REAC:R-HSA-5389840 | 6.86533657464e-12 | 1.0 | MRPL38 MRPL39 MRPL48 MRPL44 MRPS18A MRPL47 | Mitochondrial translation elongation |
| REAC:R-HSA-5368287 | 1.03629005302e-11 | 1.0 | MRPL38 MRPL39 MRPL48 MRPL44 MRPS18A MRPL47 | Mitochondrial translation |
| GO:0000315 | 1.07200971245e-10 | 1.0 | MRPL38 MRPL39 MRPL48 MRPL44 MRPS18A MRPL47 | organellar large ribosomal subunit |
| GO:0005762 | 1.07200971245e-10 | 1.0 | MRPL38 MRPL39 MRPL48 MRPL44 MRPS18A MRPL47 | mitochondrial large ribosomal subunit |
| CORUM:324 | 2.24531953346e-10 | 0.833333333333 | MRPL47 MRPL39 MRPL38 MRPL48 MRPL44 | 39S ribosomal subunit, mitochondrial |
| GO:0000313 | 2.00400849086e-09 | 1.0 | MRPL38 MRPL39 MRPL48 MRPL44 MRPS18A MRPL47 | organellar ribosome |
| GO:0005761 | 2.00400849086e-09 | 1.0 | MRPL38 MRPL39 MRPL48 MRPL44 MRPS18A MRPL47 | mitochondrial ribosome |
| GO:0015934 | 7.92035700763e-09 | 1.0 | MRPL38 MRPL39 MRPL48 MRPL44 MRPS18A MRPL47 | large ribosomal subunit |
| REAC:R-HSA-72766 | 1.02245458383e-08 | 1.0 | MRPL38 MRPL39 MRPL48 MRPL44 MRPS18A MRPL47 | Translation |
| GO:0032543 | 1.73454724604e-08 | 1.0 | MRPL38 MRPL39 MRPL48 MRPL44 MRPS18A MRPL47 | mitochondrial translation |
| GO:0140053 | 5.96587412724e-08 | 1.0 | MRPL38 MRPL39 MRPL48 MRPL44 MRPS18A MRPL47 | mitochondrial gene expression |
| GO:0044391 | 1.71747982721e-07 | 1.0 | MRPL38 MRPL39 MRPL48 MRPL44 MRPS18A MRPL47 | ribosomal subunit |
| GO:0005840 | 4.09867251823e-07 | 1.0 | MRPL38 MRPL39 MRPL48 MRPL44 MRPS18A MRPL47 | ribosome |
| GO:0098798 | 2.61027324698e-06 | 1.0 | MRPL38 MRPL39 MRPL48 MRPL44 MRPS18A MRPL47 | mitochondrial protein-containing complex |
| GO:0005743 | 1.82105970964e-05 | 1.0 | MRPL38 MRPL39 MRPL48 MRPL44 MRPS18A MRPL47 | mitochondrial inner membrane |
| GO:0005759 | 2.11940672502e-05 | 1.0 | MRPL38 MRPL39 MRPL48 MRPL44 MRPS18A MRPL47 | mitochondrial matrix |
| GO:0019866 | 2.56716471661e-05 | 1.0 | MRPL38 MRPL39 MRPL48 MRPL44 MRPS18A MRPL47 | organelle inner membrane |
| GO:0006412 | 0.000118417549116 | 1.0 | MRPL38 MRPL39 MRPL48 MRPL44 MRPS18A MRPL47 | translation |
| GO:0031966 | 0.000138329542585 | 1.0 | MRPL38 MRPL39 MRPL48 MRPL44 MRPS18A MRPL47 | mitochondrial membrane |
| GO:0043043 | 0.000141389276595 | 1.0 | MRPL38 MRPL39 MRPL48 MRPL44 MRPS18A MRPL47 | peptide biosynthetic process |
| GO:0005740 | 0.000204794763137 | 1.0 | MRPL38 MRPL39 MRPL48 MRPL44 MRPS18A MRPL47 | mitochondrial envelope |
| GO:1990904 | 0.000215533508479 | 1.0 | MRPL38 MRPL39 MRPL48 MRPL44 MRPS18A MRPL47 | ribonucleoprotein complex |
| GO:0043604 | 0.000411170968199 | 1.0 | MRPL38 MRPL39 MRPL48 MRPL44 MRPS18A MRPL47 | amide biosynthetic process |
| GO:0006518 | 0.000446172352959 | 1.0 | MRPL38 MRPL39 MRPL48 MRPL44 MRPS18A MRPL47 | peptide metabolic process |
| REAC:R-HSA-392499 | 0.000464689660191 | 1.0 | MRPL38 MRPL39 MRPL48 MRPL44 MRPS18A MRPL47 | Metabolism of proteins |
| GO:0043603 | 0.00239328344874 | 1.0 | MRPL38 MRPL39 MRPL48 MRPL44 MRPS18A MRPL47 | amide metabolic process |
| GO:0031975 | 0.00310405054115 | 1.0 | MRPL38 MRPL39 MRPL48 MRPL44 MRPS18A MRPL47 | envelope |
| GO:0031967 | 0.00310405054115 | 1.0 | MRPL38 MRPL39 MRPL48 MRPL44 MRPS18A MRPL47 | organelle envelope |
| HPA:0470682 | 0.0217107992358 | 1.0 | MRPL38 MRPL39 MRPL48 MRPL44 MRPS18A MRPL47 | skin 2; epidermal cells[>=Medium] |
| GO:0005739 | 0.022429776518 | 1.0 | MRPL38 MRPL39 MRPL48 MRPL44 MRPS18A MRPL47 | mitochondrion |
| GO:1901566 | 0.0225352456866 | 1.0 | MRPL38 MRPL39 MRPL48 MRPL44 MRPS18A MRPL47 | organonitrogen compound biosynthetic process |
| HPA:0360052 | 0.0400703067036 | 1.0 | MRPL38 MRPL39 MRPL48 MRPL44 MRPS18A MRPL47 | parathyroid gland; glandular cells[>=Medium] |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| MRPL47 | MRPL38 | 1.0 | 0.966 |
structurally_consistent (dimer)
|
hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM Guru bioplex3_WMM youn_WMM bioplex3_HCT116 fraction |
| MRPL44 | MRPL47 | 0.999 | 0.982 |
structurally_consistent (Q9BZE1)
|
hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM bioplex3_HCT116 |
| MRPL39 | MRPL47 | 0.998 | 0.996 |
structurally_consistent (Q9NWU5)
|
hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM Guru bioplex3_WMM youn_WMM bioplex3_HCT116 fraction |
| MRPL48 | MRPL47 | 0.997 | 0.992 | hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM bioplex3_HCT116 fraction | |
| MRPL48 | MRPL38 | 0.997 | 1.0 | hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM | |
| MRPL39 | MRPL44 | 0.997 | 0.994 | hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM bioplex3_HCT116 | |
| MRPS18A | MRPL38 | 0.996 | 0.96 | hein_WMM bioplex_WMM bioplex3_WMM youn_WMM bioplex3_HCT116 WMM_only | |
| MRPL48 | MRPL44 | 0.995 | 0.998 | hein_WMM bioplex_WMM bioplex3_WMM youn_WMM WMM_only | |
| MRPL39 | MRPL48 | 0.995 | 0.998 |
structurally_consistent (P09001)
|
hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM bioplex3_HCT116 fraction |
| MRPL39 | MRPL38 | 0.995 | 0.998 | hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM boldt youn_WMM bioplex3_HCT116 boldt_WMM treiber_WMM | |
| MRPS18A | MRPL39 | 0.994 | 0.82 | hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM bioplex3_HCT116 | |
| MRPL44 | MRPL38 | 0.994 | 0.994 | hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM | |
| MRPS18A | MRPL48 | 0.988 | 0.712 |
structurally_consistent (Q9P015)
|
hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 |
| MRPS18A | MRPL47 | 0.988 | 0.936 |
structurally_consistent (Q9BZE1)
|
hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM bioplex3_HCT116 |
| MRPS18A | MRPL44 | 0.975 | 0.926 |
structurally_consistent (dimer)
|
hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM bioplex3_HCT116 |
Related Complexes