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hu.MAP 3.0
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hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
List of Gene Names or Uniprot ACCs (ex. OFD1 PCM1 Q1MSJ5):
Enrichment (ex. cilium):
Protein (ex. Centrosomal protein):
Complex:
huMAP3_02472.1
Complex Portal:
CPX-19291
Confidence:
Extremely High
?
Proteins
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Genename
Protein Name
Uniprot Annotation Score
Links
IFNA6
Interferon alpha-6 (IFN-alpha-6) (Interferon alpha-54) (Interferon alpha-K) (LeIF K)
5
UniProt
NCBI
IFNA7
Interferon alpha-7 (IFN-alpha-7) (Interferon alpha-J) (LeIF J) (Interferon alpha-J1) (IFN-alpha-J1)
5
UniProt
NCBI
ISG15
Ubiquitin-like protein ISG15 (Interferon-induced 15 kDa protein) (Interferon-induced 17 kDa protein) (IP17) (Ubiquitin cross-reactive protein) (hUCRP)
5
UniProt
NCBI
UBA7
Ubiquitin-like modifier-activating enzyme 7 (Ubiquitin-activating enzyme 7) (EC 6.2.1.-) (D8) (Ubiquitin-activating enzyme E1 homolog)
5
UniProt
NCBI
Showing 1 to 4 of 4 entries
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Enrichments
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Term ID
Corrected Pval
Fraction Complex Coverage
Proteins
Term Name
REAC:R-HSA-168928
1.16721486716e-07
1.0
IFNA6 UBA7 IFNA7 ISG15
DDX58/IFIH1-mediated induction of interferon-alpha/beta
REAC:R-HSA-913531
3.6254700184e-06
1.0
IFNA6 UBA7 IFNA7 ISG15
Interferon Signaling
KEGG:04622
1.49470084516e-05
0.75
IFNA6 IFNA7 ISG15
RIG-I-like receptor signaling pathway
WP:WP4655
1.52187722416e-05
0.75
IFNA6 IFNA7 ISG15
Cytosolic DNA sensing pathway
REAC:R-HSA-909733
5.03512663474e-05
0.75
IFNA6 IFNA7 ISG15
Interferon alpha/beta signaling
REAC:R-HSA-9705671
0.00031803083943
0.75
IFNA6 IFNA7 ISG15
SARS-CoV-2 activates/modulates innate and adaptive immune responses
KEGG:05169
0.000325152133201
0.75
IFNA6 IFNA7 ISG15
Epstein-Barr virus infection
KEGG:05171
0.000459857531952
0.75
IFNA6 IFNA7 ISG15
Coronavirus disease - COVID-19
REAC:R-HSA-1280215
0.000544985136876
1.0
IFNA6 UBA7 IFNA7 ISG15
Cytokine Signaling in Immune system
WP:WP4912
0.00110807642161
0.5
IFNA6 IFNA7
SARS coronavirus and innate immunity
Showing 1 to 10 of 52 entries
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Edges
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Protein 1
Protein 2
Score
?
ProteomeHD
?
Interface Overlap
?
Evidence
?
ISG15
UBA7
0.993
0.134
structurally_consistent (dimer)
bioplex3_HEK293 bioplex3_WMM bioplex3_HCT116 WMM_only
IFNA7
ISG15
0.987
structurally_consistent (dimer)
bioplex3_HEK293 bioplex_WMM bioplex3_WMM bioplex3_HCT116 WMM_only
IFNA6
ISG15
0.986
mutually_exclusive (P01569)
bioplex_WMM bioplex3_WMM bioplex3_HCT116 WMM_only
Showing 1 to 3 of 3 entries
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Related Complexes
Genename
Complexes
IFNA6
huMAP3_02472.1
huMAP3_08774.1
huMAP3_09647.1
huMAP3_10459.1
huMAP3_11921.1
huMAP3_13851.1
IFNA7
huMAP3_02472.1
huMAP3_05551.1
huMAP3_08774.1
huMAP3_09647.1
huMAP3_10459.1
huMAP3_11921.1
huMAP3_13851.1
ISG15
huMAP3_02472.1
huMAP3_05551.1
huMAP3_08774.1
huMAP3_09647.1
huMAP3_10459.1
huMAP3_11921.1
huMAP3_13851.1
UBA7
huMAP3_02472.1
huMAP3_05551.1
huMAP3_08774.1
huMAP3_09647.1
huMAP3_10459.1
huMAP3_11921.1
huMAP3_13851.1
huMAP3_14219.1