hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_02549.1
Complex Portal: CPX-22642
Confidence: Extremely High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| SIPA1 | Signal-induced proliferation-associated protein 1 (Sipa-1) (GTPase-activating protein Spa-1) (p130 SPA-1) | 5 | UniProt NCBI |
| RACGAP1 | Rac GTPase-activating protein 1 (Male germ cell RacGap) (MgcRacGAP) (Protein CYK4 homolog) (CYK4) (HsCYK-4) | 5 | UniProt NCBI |
| SRGAP2 | SLIT-ROBO Rho GTPase-activating protein 2 (srGAP2) (Formin-binding protein 2) (Rho GTPase-activating protein 34) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-9013423 | 0.0248259565326 | 0.666666666667 | SRGAP2 RACGAP1 | RAC3 GTPase cycle |
| CORUM:7440 | 0.0499402709677 | 0.333333333333 | RACGAP1 | KIF23-RACGAP1 complex |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| RACGAP1 | SIPA1 | 0.983 | 0.042 | hein_WMM bioplex3_WMM WMM_only | |
| SRGAP2 | SIPA1 | 0.974 | 0.028 | hein_WMM bioplex3_WMM WMM_only | |
| SRGAP2 | RACGAP1 | 0.258 | 0.128 | bioplex3_WMM youn_WMM WMM_only boldt_WMM |
Related Complexes