List of Gene Names or Uniprot ACCs (ex. OFD1 PCM1 Q1MSJ5):

Enrichment (ex. cilium):

Protein (ex. Centrosomal protein):

Complex: huMAP3_02594.1

Confidence: Extremely High   ?

Proteins

Genename	Protein Name	Uniprot Annotation Score	Links
POLR2G	DNA-directed RNA polymerase II subunit RPB7 (RNA polymerase II subunit B7) (DNA-directed RNA polymerase II subunit G) (RNA polymerase II 19 kDa subunit) (RPB19)	5	UniProt   NCBI
GTF2F1	General transcription factor IIF subunit 1 (General transcription factor IIF 74 kDa subunit) (Transcription initiation factor IIF subunit alpha) (TFIIF-alpha) (Transcription initiation factor RAP74)	5	UniProt   NCBI
MYZAP	Myocardial zonula adherens protein (GRINL1A upstream protein) (Gup)	5	UniProt   NCBI
SUPT5H	Transcription elongation factor SPT5 (hSPT5) (DRB sensitivity-inducing factor 160 kDa subunit) (DSIF p160) (DRB sensitivity-inducing factor large subunit) (DSIF large subunit) (Tat-cotransactivator 1 protein) (Tat-CT1 protein)	5	UniProt   NCBI
GTF2F2	General transcription factor IIF subunit 2 (General transcription factor IIF 30 kDa subunit) (Transcription initiation factor IIF subunit beta) (TFIIF-beta) (Transcription initiation factor RAP30)	5	UniProt   NCBI



Enrichments

Term ID	Corrected Pval	Fraction Complex Coverage	Proteins	Term Name
REAC:R-HSA-167242	2.1588394976e-06	0.75	SUPT5H POLR2G GTF2F1	Abortive elongation of HIV-1 transcript in the absence of Tat
REAC:R-HSA-77075	3.64404491129e-06	0.75	SUPT5H POLR2G GTF2F1	RNA Pol II CTD phosphorylation and interaction with CE
REAC:R-HSA-167160	3.64404491129e-06	0.75	SUPT5H POLR2G GTF2F1	RNA Pol II CTD phosphorylation and interaction with CE during HIV infection
REAC:R-HSA-72086	4.59102468944e-06	0.75	SUPT5H POLR2G GTF2F1	mRNA Capping
REAC:R-HSA-167238	5.68914662089e-06	0.75	SUPT5H POLR2G GTF2F1	Pausing and recovery of Tat-mediated HIV elongation
REAC:R-HSA-167243	5.68914662089e-06	0.75	SUPT5H POLR2G GTF2F1	Tat-mediated HIV elongation arrest and recovery
REAC:R-HSA-167287	6.94957302308e-06	0.75	SUPT5H POLR2G GTF2F1	HIV elongation arrest and recovery
REAC:R-HSA-167158	6.94957302308e-06	0.75	SUPT5H POLR2G GTF2F1	Formation of the HIV-1 Early Elongation Complex
REAC:R-HSA-167290	6.94957302308e-06	0.75	SUPT5H POLR2G GTF2F1	Pausing and recovery of HIV elongation
REAC:R-HSA-113418	6.94957302308e-06	0.75	SUPT5H POLR2G GTF2F1	Formation of the Early Elongation Complex
REAC:R-HSA-167200	1.60766305396e-05	0.75	SUPT5H POLR2G GTF2F1	Formation of HIV-1 elongation complex containing HIV-1 Tat
REAC:R-HSA-167169	1.60766305396e-05	0.75	SUPT5H POLR2G GTF2F1	HIV Transcription Elongation
REAC:R-HSA-167246	1.60766305396e-05	0.75	SUPT5H POLR2G GTF2F1	Tat-mediated elongation of the HIV-1 transcript
REAC:R-HSA-167152	1.85450342998e-05	0.75	SUPT5H POLR2G GTF2F1	Formation of HIV elongation complex in the absence of HIV Tat
REAC:R-HSA-112382	4.09441910601e-05	0.75	SUPT5H POLR2G GTF2F1	Formation of RNA Pol II elongation complex
REAC:R-HSA-75955	4.09441910601e-05	0.75	SUPT5H POLR2G GTF2F1	RNA Polymerase II Transcription Elongation
REAC:R-HSA-6796648	5.03512663474e-05	0.75	SUPT5H POLR2G GTF2F1	TP53 Regulates Transcription of DNA Repair Genes
REAC:R-HSA-167172	7.00887667092e-05	0.75	SUPT5H POLR2G GTF2F1	Transcription of the HIV genome
REAC:R-HSA-6807505	8.33911915483e-05	0.75	SUPT5H POLR2G GTF2F1	RNA polymerase II transcribes snRNA genes
REAC:R-HSA-674695	0.000110531761496	0.75	SUPT5H POLR2G GTF2F1	RNA Polymerase II Pre-transcription Events
CORUM:2685	0.000465981333253	0.5	POLR2G GTF2F1	RNA polymerase II (RNAPII)
REAC:R-HSA-162599	0.000498740793897	0.75	SUPT5H POLR2G GTF2F1	Late Phase of HIV Life Cycle
REAC:R-HSA-162587	0.000650875640662	0.75	SUPT5H POLR2G GTF2F1	HIV Life Cycle
CORUM:103	0.000875235624471	0.5	POLR2G GTF2F1	RNA polymerase II holoenzyme complex
CORUM:2825	0.00107465449363	0.5	POLR2G GTF2F1	BRCA1-RNA polymerase II complex
REAC:R-HSA-8851708	0.00156635412759	0.5	POLR2G GTF2F1	Signaling by FGFR2 IIIa TM
REAC:R-HSA-162906	0.0024623188735	0.75	SUPT5H POLR2G GTF2F1	HIV Infection
REAC:R-HSA-1839126	0.00282403231951	0.5	POLR2G GTF2F1	FGFR2 mutant receptor activation
REAC:R-HSA-6803529	0.00282403231951	0.5	POLR2G GTF2F1	FGFR2 alternative splicing
REAC:R-HSA-5655253	0.00475483947495	0.5	POLR2G GTF2F1	Signaling by FGFR2 in disease
REAC:R-HSA-168325	0.0079693038543	0.5	POLR2G GTF2F1	Viral Messenger RNA Synthesis
REAC:R-HSA-3700989	0.00879681508035	0.75	SUPT5H POLR2G GTF2F1	Transcriptional Regulation by TP53
REAC:R-HSA-167162	0.0101102645678	0.5	POLR2G GTF2F1	RNA Polymerase II HIV Promoter Escape
REAC:R-HSA-75953	0.0101102645678	0.5	POLR2G GTF2F1	RNA Polymerase II Transcription Initiation
REAC:R-HSA-76042	0.0101102645678	0.5	POLR2G GTF2F1	RNA Polymerase II Transcription Initiation And Promoter Clearance
REAC:R-HSA-73776	0.0101102645678	0.5	POLR2G GTF2F1	RNA Polymerase II Promoter Escape
REAC:R-HSA-73779	0.0101102645678	0.5	POLR2G GTF2F1	RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
REAC:R-HSA-167161	0.0101102645678	0.5	POLR2G GTF2F1	HIV Transcription Initiation
REAC:R-HSA-72165	0.0115164156767	0.5	POLR2G GTF2F1	mRNA Splicing - Minor Pathway
REAC:R-HSA-1226099	0.012504459305	0.5	POLR2G GTF2F1	Signaling by FGFR in disease
REAC:R-HSA-5654738	0.0151515389193	0.5	POLR2G GTF2F1	Signaling by FGFR2
GO:0016591	0.0192043220783	0.75	MYZAP POLR2G GTF2F1	RNA polymerase II, holoenzyme
REAC:R-HSA-190236	0.019281632575	0.5	POLR2G GTF2F1	Signaling by FGFR
CORUM:153	0.0249718442456	0.25	GTF2F1	TFIIF complex (transcription factor IIF)
GO:0055029	0.048062454325	0.75	MYZAP POLR2G GTF2F1	nuclear DNA-directed RNA polymerase complex
GO:0000428	0.0496619752722	0.75	MYZAP POLR2G GTF2F1	DNA-directed RNA polymerase complex
CORUM:2860	0.049938562206	0.25	SUPT5H	DSIF complex (DRB sensitivity-inducing factor complex)
CORUM:2861	0.049938562206	0.25	SUPT5H	DSIF complex (DRB sensitivity-inducing factor complex)
CORUM:5363	0.049938562206	0.25	GTF2F1	Actin-ribonucleoprotein complex (POLR2A, GTF2F1, HNRNPU)



Edges

Protein 1	Protein 2	Score ?	ProteomeHD?	Evidence ?
GTF2F2	POLR2G	0.997	0.228	hein_WMM     bioplex3_WMM     youn_WMM     hein ()
GTF2F2	GTF2F1	0.995	0.904	hein_WMM     bioplex_WMM     bioplex3_WMM     youn_WMM     gupta_WMM     fraction     boldt_WMM
POLR2G	GTF2F1	0.995	0.264	hein_WMM     bioplex_WMM     bioplex3_WMM     youn_WMM     hein ()
POLR2G	SUPT5H	0.993	0.484	hein_WMM     bioplex_WMM     bioplex3_WMM     youn_WMM     hein ()
POLR2G	MYZAP	0.966		hein_WMM     hein ()
GTF2F2	SUPT5H	0.804	0.338	hein_WMM     youn ()     bioplex_WMM     bioplex3_WMM     youn_WMM     gupta_WMM     fraction
GTF2F2	MYZAP	0.796		hein_WMM     WMM_only
GTF2F1	MYZAP	0.641		hein_WMM     WMM_only
MYZAP	SUPT5H	0.641		hein_WMM     WMM_only
GTF2F1	SUPT5H	0.627	0.262	hein_WMM     youn ()     bioplex_WMM     bioplex3_WMM     youn_WMM     gupta_WMM     fraction





Related Complexes

Genename	Complexes
POLR2G	huMAP3_02594.1 huMAP3_04499.1 huMAP3_07454.1 huMAP3_07749.1 huMAP3_07948.1 huMAP3_09843.1 huMAP3_11018.1 huMAP3_11092.1 huMAP3_12111.1 huMAP3_14318.1
GTF2F1	huMAP3_02594.1 huMAP3_07948.1 huMAP3_11018.1
MYZAP	huMAP3_02594.1 huMAP3_07948.1 huMAP3_11018.1 huMAP3_12111.1
SUPT5H	huMAP3_02594.1 huMAP3_04499.1 huMAP3_07454.1 huMAP3_07749.1 huMAP3_07948.1 huMAP3_09843.1 huMAP3_11018.1 huMAP3_11092.1 huMAP3_12111.1
GTF2F2	huMAP3_00159.1 huMAP3_02594.1 huMAP3_04078.1 huMAP3_04499.1 huMAP3_07454.1 huMAP3_07749.1 huMAP3_07948.1 huMAP3_09843.1 huMAP3_10292.1 huMAP3_11018.1 huMAP3_11092.1