hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_02597.1
Complex Portal: CPX-22602
Confidence: Extremely High  
ProteinsGenename | Protein Name | Uniprot Annotation Score | Links |
---|---|---|---|
ESRRB | Steroid hormone receptor ERR2 (ERR beta-2) (Estrogen receptor-like 2) (Estrogen-related receptor beta) (ERR-beta) (Nuclear receptor subfamily 3 group B member 2) | 5 | UniProt   NCBI |
PPARGC1B | Peroxisome proliferator-activated receptor gamma coactivator 1-beta (PGC-1-beta) (PPAR-gamma coactivator 1-beta) (PPARGC-1-beta) (PGC-1-related estrogen receptor alpha coactivator) | 5 | UniProt   NCBI |
ESRRA | Steroid hormone receptor ERR1 (Estrogen receptor-like 1) (Estrogen-related receptor alpha) (ERR-alpha) (Nuclear receptor subfamily 3 group B member 1) | 5 | UniProt   NCBI |
ESRRG | Estrogen-related receptor gamma (ERR gamma-2) (Estrogen receptor-related protein 3) (Nuclear receptor subfamily 3 group B member 3) | 5 | UniProt   NCBI |
Enrichments
Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
---|---|---|---|---|
  REAC:R-HSA-383280 | 0.0033773260227 | 0.666666666667 | ESRRB ESRRG | Nuclear Receptor transcription pathway |
  GO:0050682 | 0.00421361424067 | 0.666666666667 | PPARGC1B ESRRG | AF-2 domain binding |
  GO:0030518 | 0.0124731132503 | 1.0 | PPARGC1B ESRRB ESRRG | intracellular steroid hormone receptor signaling pathway |
  GO:0043401 | 0.0133044554856 | 1.0 | PPARGC1B ESRRB ESRRG | steroid hormone mediated signaling pathway |
  GO:0071383 | 0.025655976884 | 1.0 | PPARGC1B ESRRB ESRRG | cellular response to steroid hormone stimulus |
  GO:0009755 | 0.0312870733704 | 1.0 | PPARGC1B ESRRB ESRRG | hormone-mediated signaling pathway |
  GO:0048545 | 0.0385436558714 | 1.0 | PPARGC1B ESRRB ESRRG | response to steroid hormone |
Edges
Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
---|---|---|---|---|---|
 ESRRB |  ESRRA | 0.992 |            |
structurally_consistent (dimer)        
|
hein_WMM     bioplex3_HEK293     bioplex3_WMM     hein ()     |
 ESRRB |  ESRRG | 0.987 |            |
structurally_consistent (dimer)        
|
bioplex3_HEK293     bioplex3_WMM     WMM_only     |
 PPARGC1B |  ESRRG | 0.987 |            |          | bioplex3_HEK293     bioplex3_WMM     WMM_only     |
 ESRRA |  ESRRG | 0.982 | 0.144           |
mutually_exclusive (O95718)        
|
bioplex3_HEK293     bioplex3_WMM     WMM_only     |
 ESRRB |  PPARGC1B | 0.415 |            |          | bioplex3_WMM     WMM_only     |
 PPARGC1B |  ESRRA | 0.415 |            |          | bioplex3_WMM     WMM_only     |
Related Complexes
Genename | Complexes |
---|---|
ESRRB | huMAP3_02597.1 huMAP3_11313.1 |
PPARGC1B | huMAP3_02597.1 huMAP3_11313.1 |
ESRRA | huMAP3_02597.1 huMAP3_11313.1 huMAP3_11700.1 |
ESRRG | huMAP3_02597.1 huMAP3_11313.1 |