hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_02615.1
Confidence: Extremely High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| AMH | Muellerian-inhibiting factor (Anti-Muellerian hormone) (AMH) (Muellerian-inhibiting substance) (MIS) | 5 | UniProt NCBI |
| SGK3 | Serine/threonine-protein kinase Sgk3 (EC 2.7.11.1) (Cytokine-independent survival kinase) (Serum/glucocorticoid-regulated kinase 3) (Serum/glucocorticoid-regulated kinase-like) | 5 | UniProt NCBI |
| AMHR2 | Anti-Muellerian hormone type-2 receptor (EC 2.7.11.30) (Anti-Muellerian hormone type II receptor) (AMH type II receptor) (MIS type II receptor) (MISRII) (MRII) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| WP:WP4842 | 0.000135842423213 | 0.666666666667 | AMH AMHR2 | Mammalian disorder of sexual development |
| HP:0031103 | 0.000189776464884 | 0.666666666667 | AMH AMHR2 | Decreased cirrculating antimullerian hormone circulation |
| HP:0031101 | 0.000265674927589 | 0.666666666667 | AMH AMHR2 | Abnormal circulating antimullerian hormone concentration |
| GO:0001880 | 0.00140460216025 | 0.666666666667 | AMH AMHR2 | Mullerian duct regression |
| REAC:R-HSA-201451 | 0.00204339075673 | 0.666666666667 | AMH AMHR2 | Signaling by BMP |
| KEGG:04350 | 0.0028446957576 | 0.666666666667 | AMH AMHR2 | TGF-beta signaling pathway |
| GO:1990262 | 0.00421361424067 | 0.666666666667 | AMH AMHR2 | anti-Mullerian hormone signaling pathway |
| HP:0000037 | 0.00587635932745 | 0.666666666667 | AMH AMHR2 | Male pseudohermaphroditism |
| WP:WP5316 | 0.00929774738496 | 0.666666666667 | AMH AMHR2 | Primary ovarian insufficiency |
| HP:0008689 | 0.0125029572242 | 0.666666666667 | AMH AMHR2 | Bilateral cryptorchidism |
| KEGG:04060 | 0.0146065267115 | 0.666666666667 | AMH AMHR2 | Cytokine-cytokine receptor interaction |
| GO:0060033 | 0.0210651876021 | 0.666666666667 | AMH AMHR2 | anatomical structure regression |
| REAC:R-HSA-9006936 | 0.0392065258044 | 0.666666666667 | AMH AMHR2 | Signaling by TGFB family members |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| SGK3 | AMHR2 | 1.0 | bioplex3_HEK293 bioplex3_WMM bioplex3_HCT116 WMM_only | |
| AMH | AMHR2 | 0.988 | bioplex3_HEK293 bioplex3_WMM WMM_only | |
| AMH | SGK3 | 0.278 | bioplex3_WMM WMM_only |
Related Complexes