hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_02617.1
Complex Portal: CPX-15493
Confidence: Extremely High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| IRF3 | Interferon regulatory factor 3 (IRF-3) | 5 | UniProt NCBI |
| AHSA1 | Activator of 90 kDa heat shock protein ATPase homolog 1 (AHA1) (p38) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| WP:WP5187 | 0.0373151717536 | 0.5 | IRF3 | mRNA vaccine activation of dendritic cell and induction of IFN 1 |
| WP:WP5116 | 0.049750157242 | 0.5 | IRF3 | SARS CoV 2 B 1 1 7 variant antagonises innate immune activation |
| REAC:R-HSA-1606341 | 0.0499419797295 | 0.5 | IRF3 | IRF3 mediated activation of type 1 IFN |
| CORUM:299 | 0.0499419797295 | 0.5 | IRF3 | IRF3-CBP complex |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| IRF3 | AHSA1 | 0.976 | 0.158 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 |
Related Complexes