hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_02619.1
Complex Portal: CPX-14604
Confidence: Extremely High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| MPPE1 | Metallophosphoesterase 1 (EC 3.1.-.-) (Post-GPI attachment to proteins factor 5) | 5 | UniProt NCBI |
| UGT3A2 | UDP-glucuronosyltransferase 3A2 (UDPGT 3A2) (EC 2.4.1.17) | 4 | UniProt NCBI |
| EDEM1 | ER degradation-enhancing alpha-mannosidase-like protein 1 | 5 | UniProt NCBI |
| PIGB | GPI mannosyltransferase 3 (EC 2.4.1.-) (GPI mannosyltransferase III) (GPI-MT-III) (Phosphatidylinositol-glycan biosynthesis class B protein) (PIG-B) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| KEGG:00563 | 0.000525813091528 | 0.5 | PIGB MPPE1 | Glycosylphosphatidylinositol (GPI)-anchor biosynthesis |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| EDEM1 | MPPE1 | 0.982 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | ||
| PIGB | MPPE1 | 0.966 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | ||
| MPPE1 | UGT3A2 | 0.958 |
structurally_consistent (dimer)
|
bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | |
| PIGB | UGT3A2 | 0.435 | bioplex_WMM bioplex3_WMM WMM_only | ||
| PIGB | EDEM1 | 0.156 | bioplex_WMM bioplex3_WMM WMM_only | ||
| EDEM1 | UGT3A2 | 0.107 | bioplex_WMM bioplex3_WMM WMM_only |
Related Complexes