hu.MAP 3.0: Complex View

Genename	Protein Name	Uniprot Annotation Score	Links
IDH1	Isocitrate dehydrogenase [NADP] cytoplasmic (IDH) (IDH1) (EC 1.1.1.42) (Cytosolic NADP-isocitrate dehydrogenase) (IDPc) (NADP(+)-specific ICDH) (Oxalosuccinate decarboxylase)	5	UniProt NCBI
PLS3	Plastin-3 (T-plastin)	5	UniProt NCBI

Term ID	Corrected Pval	Fraction Complex Coverage	Proteins	Term Name
REAC:R-HSA-2978092	0.0124859221228	1.0	IDH1	Abnormal conversion of 2-oxoglutarate to 2-hydroxyglutarate
REAC:R-HSA-389542	0.0124859221228	1.0	IDH1	NADPH regeneration
CORUM:404	0.0249718442455	1.0	IDH1	Isocitrate dehydrogenase [NADP], cytoplasmic
WP:WP3585	0.0318034510379	1.0	IDH1	Cytosine methylation
REAC:R-HSA-9818025	0.0374577663684	1.0	IDH1	NFE2L2 regulating TCA cycle genes
HPA:0640411	0.0476886552836	1.0	IDH1	endometrium; macrophages[>=Low]
HPA:0640412	0.0476886552836	1.0	IDH1	endometrium; macrophages[>=Medium]
KEGG:00020	0.0481851079105	1.0	IDH1	Citrate cycle (TCA cycle)
KEGG:01210	0.0481851079105	1.0	IDH1	2-Oxocarboxylic acid metabolism
HP:0004820	0.0495817777049	1.0	IDH1	Acute myelomonocytic leukemia
HP:0011681	0.0495817777049	1.0	IDH1	Subarterial ventricular septal defect
HP:0030294	0.0495817777049	1.0	IDH1	Metaphyseal chondromatosis of tibia
HP:0030295	0.0495817777049	1.0	IDH1	Metaphyseal chondromatosis of femur
HP:0030296	0.0495817777049	1.0	IDH1	Metaphyseal chondromatosis of radius
HP:0030297	0.0495817777049	1.0	IDH1	Metaphyseal chondromatosis of ulna

Protein 1	Protein 2	Score	ProteomeHD	Interface Overlap	Evidence
IDH1	PLS3	0.956	0.264		bioplex_WMM Guru bioplex3_WMM youn_WMM gupta_WMM fraction boldt_WMM

Genename	Complexes
IDH1	huMAP3_00561.1 huMAP3_01475.1 huMAP3_02650.1 huMAP3_09400.1 huMAP3_10900.1 huMAP3_12355.1
PLS3	huMAP3_02650.1 huMAP3_03533.1 huMAP3_05481.1 huMAP3_07456.1 huMAP3_10281.1 huMAP3_10900.1 huMAP3_14442.1