hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_02651.1
Complex Portal: CPX-13596
Confidence: Extremely High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| MAPK1 | Mitogen-activated protein kinase 1 (MAP kinase 1) (MAPK 1) (EC 2.7.11.24) (ERT1) (Extracellular signal-regulated kinase 2) (ERK-2) (MAP kinase isoform p42) (p42-MAPK) (Mitogen-activated protein kinase 2) (MAP kinase 2) (MAPK 2) | 5 | UniProt NCBI |
| PTPRR | Receptor-type tyrosine-protein phosphatase R (R-PTP-R) (EC 3.1.3.48) (Ch-1PTPase) (NC-PTPCOM1) (Protein-tyrosine phosphatase PCPTP1) | 5 | UniProt NCBI |
| DHPS | Deoxyhypusine synthase (DHS) (EC 2.5.1.46) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| HP:0034208 | 0.0499436884913 | 0.5 | DHPS | Fetal intracranial hemorrhage |
| HP:0034210 | 0.0499436884913 | 0.5 | DHPS | Fetal intraventricular hemorrhage |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| DHPS | MAPK1 | 0.998 | 0.024 |
mutually_exclusive (P27361)
structurally_consistent (dimer) |
bioplex3_HEK293 bioplex_WMM bioplex3_WMM youn_WMM bioplex3_HCT116 WMM_only |
| MAPK1 | PTPRR | 0.977 |
structurally_consistent (dimer)
|
bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 |
Related Complexes