hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_02652.1
Complex Portal: CPX-19415
Confidence: Extremely High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| ORC6 | Origin recognition complex subunit 6 | 5 | UniProt NCBI |
| PSPC1 | Paraspeckle component 1 (Paraspeckle protein 1) | 5 | UniProt NCBI |
| NONO | Non-POU domain-containing octamer-binding protein (NonO protein) (54 kDa nuclear RNA- and DNA-binding protein) (p54(nrb)) (p54nrb) (55 kDa nuclear protein) (NMT55) (DNA-binding p52/p100 complex, 52 kDa subunit) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:7285 | 5.12534978153e-05 | 0.666666666667 | PSPC1 NONO | HEXIM1-DNA-PK-paraspeckle components-ribonucleoprotein complex |
| HPA:0570783 | 0.0059487071562 | 1.0 | PSPC1 ORC6 NONO | testis; preleptotene spermatocytes[High] |
| WP:WP3594 | 0.0141264814409 | 0.666666666667 | PSPC1 NONO | Circadian rhythm genes |
| CORUM:330 | 0.0249718442456 | 0.333333333333 | NONO | PSF-p54(nrb) complex |
| CORUM:1760 | 0.0249718442456 | 0.333333333333 | NONO | TOP1-PSF-P54 complex |
| HP:5201016 | 0.0349981079563 | 0.666666666667 | ORC6 NONO | Submucous cleft palate |
| GO:0001650 | 0.039413061643 | 1.0 | PSPC1 ORC6 NONO | fibrillar center |
| HPA:0570782 | 0.0440355061936 | 1.0 | PSPC1 ORC6 NONO | testis; preleptotene spermatocytes[>=Medium] |
| CORUM:335 | 0.0499402709677 | 0.333333333333 | NONO | p54(nrb)-PSF-matrin3 complex |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| PSPC1 | NONO | 1.0 | 0.62 |
structurally_consistent (dimer)
|
hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM boldt bioplex3_HCT116 fraction boldt_WMM treiber_WMM |
| ORC6 | NONO | 0.972 | 0.22 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | |
| ORC6 | PSPC1 | 0.957 | 0.092 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM |
Related Complexes