hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_02681.1
Confidence: Extremely High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| AMH | Muellerian-inhibiting factor (Anti-Muellerian hormone) (AMH) (Muellerian-inhibiting substance) (MIS) | 5 | UniProt NCBI |
| AMHR2 | Anti-Muellerian hormone type-2 receptor (EC 2.7.11.30) (Anti-Muellerian hormone type II receptor) (AMH type II receptor) (MIS type II receptor) (MISRII) (MRII) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| WP:WP4842 | 5.10764421909e-05 | 1.0 | AMH AMHR2 | Mammalian disorder of sexual development |
| HP:0031103 | 5.12628525639e-05 | 1.0 | AMH AMHR2 | Decreased cirrculating antimullerian hormone circulation |
| HP:0031101 | 7.17679935894e-05 | 1.0 | AMH AMHR2 | Abnormal circulating antimullerian hormone concentration |
| GO:0001880 | 0.000468200720083 | 1.0 | AMH AMHR2 | Mullerian duct regression |
| REAC:R-HSA-201451 | 0.000512628525639 | 1.0 | AMH AMHR2 | Signaling by BMP |
| KEGG:04350 | 0.000608173227025 | 1.0 | AMH AMHR2 | TGF-beta signaling pathway |
| GO:1990262 | 0.00140460216025 | 1.0 | AMH AMHR2 | anti-Mullerian hormone signaling pathway |
| HP:0000037 | 0.00158914842948 | 1.0 | AMH AMHR2 | Male pseudohermaphroditism |
| KEGG:04060 | 0.0031385705215 | 1.0 | AMH AMHR2 | Cytokine-cytokine receptor interaction |
| HP:0008689 | 0.00338334826922 | 1.0 | AMH AMHR2 | Bilateral cryptorchidism |
| WP:WP5316 | 0.00351405922273 | 1.0 | AMH AMHR2 | Primary ovarian insufficiency |
| GO:0060033 | 0.00702301080125 | 1.0 | AMH AMHR2 | anatomical structure regression |
| REAC:R-HSA-9006936 | 0.0098732254038 | 1.0 | AMH AMHR2 | Signaling by TGFB family members |
| HP:0003251 | 0.0212433261025 | 1.0 | AMH AMHR2 | Male infertility |
| HP:0012041 | 0.0318376489657 | 1.0 | AMH AMHR2 | Decreased fertility in males |
| WP:WP4814 | 0.0435328773163 | 0.5 | AMH | Somatic sex determination |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| AMH | AMHR2 | 0.988 | bioplex3_HEK293 bioplex3_WMM WMM_only |
Related Complexes
| Genename | Complexes |
|---|---|
| AMH | huMAP3_02615.1 huMAP3_02681.1 huMAP3_06702.1 huMAP3_09271.1 huMAP3_13875.1 |
| AMHR2 | huMAP3_02615.1 huMAP3_02681.1 huMAP3_04963.1 huMAP3_09271.1 huMAP3_13837.1 huMAP3_14850.1 |