hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_02698.1
Confidence: Extremely High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| CXXC1 | CXXC-type zinc finger protein 1 (CpG-binding protein) (PHD finger and CXXC domain-containing protein 1) | 5 | UniProt NCBI |
| SETD1A | Histone-lysine N-methyltransferase SETD1A (EC 2.1.1.364) (Lysine N-methyltransferase 2F) (SET domain-containing protein 1A) (hSET1A) (Set1/Ash2 histone methyltransferase complex subunit SET1) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:2731 | 2.56314262819e-05 | 1.0 | SETD1A CXXC1 | Set1A complex |
| CORUM:6469 | 7.68942788458e-05 | 1.0 | SETD1A CXXC1 | Set1A complex |
| REAC:R-HSA-9772755 | 0.00133283416666 | 1.0 | SETD1A CXXC1 | Formation of WDR5-containing histone-modifying complexes |
| REAC:R-HSA-212165 | 0.0248368520672 | 1.0 | SETD1A CXXC1 | Epigenetic regulation of gene expression |
| GO:0048188 | 0.0426062655276 | 1.0 | SETD1A CXXC1 | Set1C/COMPASS complex |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| CXXC1 | SETD1A | 1.0 | 0.46 | hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM hein () fraction |
Related Complexes