hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_02702.1
Confidence: Extremely High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| HOMER3 | Homer protein homolog 3 (Homer-3) | 5 | UniProt NCBI |
| HOMER2 | Homer protein homolog 2 (Homer-2) (Cupidin) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| KEGG:04724 | 0.000526725810094 | 1.0 | HOMER3 HOMER2 | Glutamatergic synapse |
| KEGG:04068 | 0.00102874102663 | 1.0 | HOMER3 HOMER2 | FoxO signaling pathway |
| WP:WP5417 | 0.00155570330173 | 1.0 | HOMER3 HOMER2 | Cell lineage map for neuronal differentiation |
| REAC:R-HSA-6794361 | 0.00176856841345 | 1.0 | HOMER3 HOMER2 | Neurexins and neuroligins |
| REAC:R-HSA-6794362 | 0.00412665963139 | 1.0 | HOMER3 HOMER2 | Protein-protein interactions at synapses |
| GO:0007216 | 0.00702301080125 | 1.0 | HOMER3 HOMER2 | G protein-coupled glutamate receptor signaling pathway |
| GO:2001256 | 0.00702301080125 | 1.0 | HOMER3 HOMER2 | regulation of store-operated calcium entry |
| GO:0035256 | 0.00983221512175 | 1.0 | HOMER3 HOMER2 | G protein-coupled glutamate receptor binding |
| WP:WP5420 | 0.0144418640295 | 1.0 | HOMER3 HOMER2 | ADHD and autism ASD linked metabolic pathways and SNP |
| GO:0002115 | 0.0210690324038 | 1.0 | HOMER3 HOMER2 | store-operated calcium entry |
| GO:0070885 | 0.0210690324038 | 1.0 | HOMER3 HOMER2 | negative regulation of calcineurin-NFAT signaling cascade |
| GO:0106057 | 0.0210690324038 | 1.0 | HOMER3 HOMER2 | negative regulation of calcineurin-mediated signaling |
| GO:0050849 | 0.0365196561665 | 1.0 | HOMER3 HOMER2 | negative regulation of calcium-mediated signaling |
| CORUM:74 | 0.0499419797295 | 0.5 | HOMER3 | HOMER3-IP3R-TRPC1 complex |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| HOMER3 | HOMER2 | 0.998 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM |
Related Complexes