hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_02713.1
Confidence: Extremely High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| ING5 | Inhibitor of growth protein 5 (p28ING5) | 5 | UniProt NCBI |
| KAT6A | Histone acetyltransferase KAT6A (EC 2.3.1.48) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3) (MYST-3) (Monocytic leukemia zinc finger protein) (Runt-related transcription factor-binding protein 2) (Zinc finger protein 220) | 5 | UniProt NCBI |
| BRPF1 | Peregrin (Bromodomain and PHD finger-containing protein 1) (Protein Br140) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:2859 | 2.33868713081e-09 | 1.0 | ING5 BRPF1 KAT6A | ING5 (BRPF1, MOZ, MORF) complex |
| REAC:R-HSA-6804758 | 1.89440469306e-06 | 1.0 | ING5 BRPF1 KAT6A | Regulation of TP53 Activity through Acetylation |
| GO:0070776 | 3.36420143768e-06 | 1.0 | ING5 BRPF1 KAT6A | MOZ/MORF histone acetyltransferase complex |
| GO:0070775 | 5.38272230028e-06 | 1.0 | ING5 BRPF1 KAT6A | H3 histone acetyltransferase complex |
| CORUM:7252 | 3.41705576683e-05 | 0.666666666667 | ING5 KAT6A | ING5 (BRPF2, MOZ, MORF) complex |
| CORUM:7253 | 3.41705576683e-05 | 0.666666666667 | ING5 KAT6A | ING5 (BRPF3, MOZ, MORF) complex |
| REAC:R-HSA-3214847 | 0.00016307931474 | 1.0 | ING5 BRPF1 KAT6A | HATs acetylate histones |
| REAC:R-HSA-5633007 | 0.000267736308591 | 1.0 | ING5 BRPF1 KAT6A | Regulation of TP53 Activity |
| REAC:R-HSA-3247509 | 0.00120056730917 | 1.0 | ING5 BRPF1 KAT6A | Chromatin modifying enzymes |
| REAC:R-HSA-4839726 | 0.00120056730917 | 1.0 | ING5 BRPF1 KAT6A | Chromatin organization |
| REAC:R-HSA-3700989 | 0.00297633187542 | 1.0 | ING5 BRPF1 KAT6A | Transcriptional Regulation by TP53 |
| GO:0000123 | 0.0105478288276 | 1.0 | ING5 BRPF1 KAT6A | histone acetyltransferase complex |
| GO:0031248 | 0.0146194737676 | 1.0 | ING5 BRPF1 KAT6A | protein acetyltransferase complex |
| GO:1902493 | 0.0146194737676 | 1.0 | ING5 BRPF1 KAT6A | acetyltransferase complex |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| ING5 | KAT6A | 0.998 | 0.266 | hein_WMM bioplex3_HEK293 bioplex_WMM bioplex3_WMM hein () bioplex3_HCT116 |
| BRPF1 | ING5 | 0.998 | 0.376 | bioplex3_HEK293 bioplex_WMM bioplex3_WMM bioplex3_HCT116 WMM_only |
| BRPF1 | KAT6A | 0.719 | 0.218 | bioplex_WMM bioplex3_WMM youn_WMM WMM_only |
Related Complexes