hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_02715.1
Confidence: Extremely High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| PEMT | Phosphatidylethanolamine N-methyltransferase (PEAMT) (PEMT) (EC 2.1.1.17) (EC 2.1.1.71) (PEMT2) (Phospholipid methyltransferase) (PLMT) | 5 | UniProt NCBI |
| PMEL | Melanocyte protein PMEL (ME20-M) (ME20M) (Melanocyte protein Pmel 17) (Melanocytes lineage-specific antigen GP100) (Melanoma-associated ME20 antigen) (P1) (P100) (Premelanosome protein) (Silver locus protein homolog) [Cleaved into: M-alpha (95 kDa melanocyte-specific secreted glycoprotein) (P26) (Secreted melanoma-associated ME20 antigen) (ME20-S) (ME20S); M-beta] | 5 | UniProt NCBI |
| SLC40A1 | Solute carrier family 40 member 1 (Ferroportin-1) (Iron-regulated transporter 1) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| WP:WP528 | 0.0413734636003 | 0.333333333333 | PEMT | Acetylcholine synthesis |
| REAC:R-HSA-5655799 | 0.0498224659464 | 0.333333333333 | SLC40A1 | Defective SLC40A1 causes hemochromatosis 4 (HFE4) (duodenum) |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| PEMT | PMEL | 0.999 | 0.05 | bioplex3_WMM bioplex3_HCT116 WMM_only |
| PEMT | SLC40A1 | 0.998 | bioplex3_WMM bioplex3_HCT116 WMM_only | |
| SLC40A1 | PMEL | 0.902 | bioplex3_WMM WMM_only |
Related Complexes