hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_02728.1
Confidence: Extremely High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| PCYT1A | Choline-phosphate cytidylyltransferase A (EC 2.7.7.15) (CCT-alpha) (CTP:phosphocholine cytidylyltransferase A) (CCT A) (CT A) (Phosphorylcholine transferase A) | 5 | UniProt NCBI |
| DNAH10 | Dynein axonemal heavy chain 10 (Axonemal beta dynein heavy chain 10) (Ciliary dynein heavy chain 10) | 5 | UniProt NCBI |
| PCYT1B | Choline-phosphate cytidylyltransferase B (EC 2.7.7.15) (CCT-beta) (CTP:phosphocholine cytidylyltransferase B) (CCT B) (CT B) (Phosphorylcholine transferase B) | 5 | UniProt NCBI |
| IP6K3 | Inositol hexakisphosphate kinase 3 (InsP6 kinase 3) (EC 2.7.4.21) (Inositol hexaphosphate kinase 3) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| KEGG:00440 | 2.50753160682e-05 | 0.5 | PCYT1A PCYT1B | Phosphonate and phosphinate metabolism |
| WP:WP3933 | 0.000198998246169 | 0.5 | PCYT1A PCYT1B | Kennedy pathway from sphingolipids |
| WP:WP3940 | 0.0022974831852 | 0.5 | PCYT1A PCYT1B | One carbon metabolism and related pathways |
| REAC:R-HSA-1483191 | 0.00258893271292 | 0.5 | PCYT1A PCYT1B | Synthesis of PC |
| GO:0004105 | 0.0028092043205 | 0.5 | PCYT1A PCYT1B | choline-phosphate cytidylyltransferase activity |
| WP:WP2525 | 0.00377411060353 | 0.5 | PCYT1A PCYT1B | Trans sulfuration one carbon metabolism and related pathways |
| KEGG:00564 | 0.00767363259098 | 0.5 | PCYT1A PCYT1B | Glycerophospholipid metabolism |
| KEGG:05231 | 0.00847251296121 | 0.5 | PCYT1A PCYT1B | Choline metabolism in cancer |
| GO:0006657 | 0.0168521501606 | 0.5 | PCYT1A PCYT1B | CDP-choline pathway |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| IP6K3 | PCYT1A | 0.984 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | |
| PCYT1A | PCYT1B | 0.983 | bioplex3_HEK293 bioplex3_WMM WMM_only | |
| PCYT1A | DNAH10 | 0.978 | 0.034 | bioplex3_HEK293 bioplex3_WMM youn_WMM WMM_only |
| DNAH10 | PCYT1B | 0.415 | bioplex3_WMM WMM_only |
Related Complexes
| Genename | Complexes |
|---|---|
| PCYT1A | huMAP3_02131.1 huMAP3_02728.1 huMAP3_04069.1 huMAP3_05857.1 |
| DNAH10 | huMAP3_02728.1 huMAP3_04069.1 |
| PCYT1B | huMAP3_02728.1 huMAP3_04069.1 huMAP3_05857.1 |
| IP6K3 | huMAP3_00884.1 huMAP3_02131.1 huMAP3_02728.1 huMAP3_05281.1 huMAP3_13471.1 huMAP3_13930.1 huMAP3_14835.1 |