hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_02739.1
Confidence: Extremely High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| SETD2 | Histone-lysine N-methyltransferase SETD2 (EC 2.1.1.359) (HIF-1) (Huntingtin yeast partner B) (Huntingtin-interacting protein 1) (HIP-1) (Huntingtin-interacting protein B) (Lysine N-methyltransferase 3A) (Protein-lysine N-methyltransferase SETD2) (EC 2.1.1.-) (SET domain-containing protein 2) (hSET2) (p231HBP) | 5 | UniProt NCBI |
| RSBN1L | Lysine-specific demethylase RSBN1L (EC 1.14.11.-) (Round spermatid basic protein 1-like protein) | 3 | UniProt NCBI |
| NKTR | NK-tumor recognition protein (NK-TR protein) (Natural-killer cells cyclophilin-related protein) (Peptidyl-prolyl cis-trans isomerase NKTR) (PPIase) (EC 5.2.1.8) (Rotamase) | 5 | UniProt NCBI |
| ACIN1 | Apoptotic chromatin condensation inducer in the nucleus (Acinus) | 5 | UniProt NCBI |
| RNPS1 | RNA-binding protein with serine-rich domain 1 (SR-related protein LDC2) | 5 | UniProt NCBI |
| GPATCH8 | G patch domain-containing protein 8 | 4 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:760 | 5.12534978153e-05 | 0.333333333333 | RNPS1 ACIN1 | Apoptosis- and splicing-associated protein complex (ASAP-L), SAP18, RNPS1, Acinus-L |
| KEGG:03015 | 0.029291198851 | 0.333333333333 | RNPS1 ACIN1 | mRNA surveillance pathway |
| KEGG:03013 | 0.0360561963985 | 0.333333333333 | RNPS1 ACIN1 | Nucleocytoplasmic transport |
| GO:0061574 | 0.042122686785 | 0.333333333333 | RNPS1 ACIN1 | ASAP complex |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| RNPS1 | GPATCH8 | 0.999 | 0.376 | bioplex3_HEK293 bioplex_WMM bioplex3_WMM youn_WMM hein () bioplex3_HCT116 gupta_WMM fraction |
| ACIN1 | RNPS1 | 0.998 | 0.92 | bioplex3_HEK293 bioplex_WMM bioplex3_WMM youn_WMM bioplex3_HCT116 gupta_WMM fraction |
| ACIN1 | NKTR | 0.996 | 0.362 | hein_WMM bioplex_WMM bioplex3_WMM WMM_only |
| RNPS1 | SETD2 | 0.994 | 0.126 | bioplex3_HEK293 bioplex_WMM bioplex3_WMM youn_WMM bioplex3_HCT116 gupta_WMM WMM_only |
| RNPS1 | NKTR | 0.994 | 0.316 | bioplex_WMM bioplex3_WMM bioplex3_HCT116 boldt_WMM WMM_only |
| RNPS1 | RSBN1L | 0.988 | 0.092 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM bioplex3_HCT116 |
| SETD2 | GPATCH8 | 0.929 | 0.084 | bioplex_WMM bioplex3_WMM youn_WMM WMM_only boldt_WMM |
| NKTR | GPATCH8 | 0.928 | 0.178 | bioplex_WMM bioplex3_WMM WMM_only |
| ACIN1 | GPATCH8 | 0.886 | 0.35 | bioplex_WMM bioplex3_WMM youn_WMM gupta_WMM fraction |
| NKTR | SETD2 | 0.641 | 0.204 | bioplex_WMM bioplex3_WMM WMM_only |
| NKTR | RSBN1L | 0.594 | 0.106 | bioplex_WMM bioplex3_WMM WMM_only |
| ACIN1 | SETD2 | 0.468 | 0.166 | bioplex_WMM bioplex3_WMM youn_WMM fraction |
| RSBN1L | GPATCH8 | 0.33 | 0.056 | bioplex3_WMM youn_WMM WMM_only |
| ACIN1 | RSBN1L | 0.201 | 0.226 | bioplex_WMM bioplex3_WMM youn_WMM WMM_only |
| RSBN1L | SETD2 | 0.172 | 0.158 | bioplex3_WMM youn_WMM WMM_only |
Related Complexes