hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_02778.1
Complex Portal: CPX-18663
Confidence: Extremely High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| FAM98C | Protein FAM98C | 4 | UniProt NCBI |
| DDX1 | ATP-dependent RNA helicase DDX1 (EC 3.6.4.13) (DEAD box protein 1) (DEAD box protein retinoblastoma) (DBP-RB) | 5 | UniProt NCBI |
| C2orf49 | Ashwin | 4 | UniProt NCBI |
| FAM98B | Protein FAM98B | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| GO:0072669 | 1.84188417064e-09 | 1.0 | FAM98C C2orf49 FAM98B DDX1 | tRNA-splicing ligase complex |
| CORUM:6301 | 7.01534115619e-09 | 0.75 | DDX1 FAM98B C2orf49 | tRNA Splicing Ligase Complex |
| REAC:R-HSA-6784531 | 3.67150180564e-05 | 0.75 | DDX1 FAM98B C2orf49 | tRNA processing in the nucleus |
| GO:0006388 | 6.34131776058e-05 | 0.75 | DDX1 FAM98B C2orf49 | tRNA splicing, via endonucleolytic cleavage and ligation |
| GO:0000394 | 8.45465618902e-05 | 0.75 | DDX1 FAM98B C2orf49 | RNA splicing, via endonucleolytic cleavage and ligation |
| REAC:R-HSA-72306 | 0.000219007946647 | 0.75 | DDX1 FAM98B C2orf49 | tRNA processing |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| DDX1 | FAM98B | 1.0 | 0.776 | youn () bioplex3_HEK293 bioplex_WMM Guru bioplex3_WMM youn_WMM Malo bioplex3_HCT116 gupta_WMM fraction treiber_WMM | |
| DDX1 | C2orf49 | 0.999 | 0.052 | bioplex3_HEK293 bioplex_WMM bioplex3_WMM bioplex3_HCT116 WMM_only | |
| DDX1 | FAM98C | 0.996 | 0.248 | youn () bioplex3_HEK293 bioplex3_WMM bioplex3_HCT116 WMM_only | |
| C2orf49 | FAM98B | 0.911 | 0.06 | bioplex_WMM bioplex3_WMM bioplex3_HCT116 WMM_only | |
| C2orf49 | FAM98C | 0.472 | 0.086 | bioplex3_WMM WMM_only | |
| FAM98B | FAM98C | 0.402 | 0.074 |
mutually_exclusive (Q9Y224)
|
bioplex3_WMM youn_WMM WMM_only |
Related Complexes