hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_02784.1
Confidence: Extremely High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| G3BP2 | Ras GTPase-activating protein-binding protein 2 (G3BP-2) (GAP SH3 domain-binding protein 2) | 5 | UniProt NCBI |
| USP10 | Ubiquitin carboxyl-terminal hydrolase 10 (EC 3.4.19.12) (Deubiquitinating enzyme 10) (Ubiquitin thioesterase 10) (Ubiquitin-specific-processing protease 10) | 5 | UniProt NCBI |
| CAPRIN1 | Caprin-1 (Cell cycle-associated protein 1) (Cytoplasmic activation- and proliferation-associated protein 1) (GPI-anchored membrane protein 1) (GPI-anchored protein p137) (GPI-p137) (p137GPI) (Membrane component chromosome 11 surface marker 1) (RNA granule protein 105) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| GO:0062028 | 9.61200410764e-07 | 1.0 | G3BP2 USP10 CAPRIN1 | regulation of stress granule assembly |
| GO:0034063 | 0.000249912106799 | 1.0 | G3BP2 USP10 CAPRIN1 | stress granule assembly |
| GO:0062029 | 0.00842684400117 | 0.666666666667 | G3BP2 CAPRIN1 | positive regulation of stress granule assembly |
| HPA:0310433 | 0.0139863689225 | 1.0 | G3BP2 USP10 CAPRIN1 | lymph node; germinal center cells[High] |
| HPA:0330223 | 0.0265048582464 | 1.0 | G3BP2 USP10 CAPRIN1 | oral mucosa; squamous epithelial cells[High] |
| HPA:0600433 | 0.0311676675212 | 1.0 | G3BP2 USP10 CAPRIN1 | tonsil; germinal center cells[High] |
| HPA:0250133 | 0.0339994352931 | 1.0 | G3BP2 USP10 CAPRIN1 | hippocampus; neuronal cells[High] |
| HPA:0600443 | 0.0359795023139 | 1.0 | G3BP2 USP10 CAPRIN1 | tonsil; non-germinal center cells[High] |
| HPA:0390053 | 0.040266084773 | 1.0 | G3BP2 USP10 CAPRIN1 | prostate; glandular cells[High] |
| HPA:0170053 | 0.0406627923068 | 1.0 | G3BP2 USP10 CAPRIN1 | endometrium 2; glandular cells[High] |
| HPA:0050053 | 0.0436171192214 | 1.0 | G3BP2 USP10 CAPRIN1 | breast; glandular cells[High] |
| HPA:0040083 | 0.0485912095421 | 1.0 | G3BP2 USP10 CAPRIN1 | bone marrow; hematopoietic cells[High] |
| CORUM:7357 | 0.0499402709677 | 0.333333333333 | G3BP2 | TRIM25-G3BP2 complex |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| G3BP2 | USP10 | 1.0 | 0.144 | hein_WMM youn () bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM bioplex3_HCT116 gupta_WMM treiber_WMM |
| CAPRIN1 | G3BP2 | 1.0 | 0.212 | youn () bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM bioplex3_HCT116 gupta_WMM fraction treiber_WMM |
| CAPRIN1 | USP10 | 0.989 | 0.48 | hein_WMM youn () bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM bioplex3_HCT116 gupta_WMM treiber_WMM |
Related Complexes