hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_02790.1
Complex Portal: CPX-22063
Confidence: Extremely High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| ZNF521 | Zinc finger protein 521 (Early hematopoietic zinc finger protein) (LYST-interacting protein 3) | 5 | UniProt NCBI |
| MTA1 | Metastasis-associated protein MTA1 | 5 | UniProt NCBI |
| ERCC6 | DNA excision repair protein ERCC-6 (EC 3.6.4.-) (ATP-dependent helicase ERCC6) (Cockayne syndrome protein CSB) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-73762 | 0.00735562020533 | 0.666666666667 | MTA1 ERCC6 | RNA Polymerase I Transcription Initiation |
| REAC:R-HSA-427389 | 0.0137071284674 | 0.666666666667 | MTA1 ERCC6 | ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression |
| REAC:R-HSA-5250913 | 0.0290482612381 | 0.666666666667 | MTA1 ERCC6 | Positive epigenetic regulation of rRNA expression |
| REAC:R-HSA-73854 | 0.0322661899036 | 0.666666666667 | MTA1 ERCC6 | RNA Polymerase I Promoter Clearance |
| REAC:R-HSA-73864 | 0.0329299631783 | 0.666666666667 | MTA1 ERCC6 | RNA Polymerase I Transcription |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| ZNF521 | MTA1 | 0.993 | 0.196 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | |
| MTA1 | ERCC6 | 0.972 | 0.208 | hein_WMM bioplex3_WMM hein () | |
| ZNF521 | ERCC6 | 0.078 | 0.084 | bioplex3_WMM WMM_only |
Related Complexes