hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_02812.1
Complex Portal: CPX-14928
Confidence: Extremely High  
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| IL36A | Interleukin-36 alpha (FIL1 epsilon) (Interleukin-1 epsilon) (IL-1 epsilon) (Interleukin-1 family member 6) (IL-1F6) | 5 | UniProt   NCBI |
| RNF40 | E3 ubiquitin-protein ligase BRE1B (BRE1-B) (EC 2.3.2.27) (95 kDa retinoblastoma-associated protein) (RBP95) (RING finger protein 40) (RING-type E3 ubiquitin transferase BRE1B) | 5 | UniProt   NCBI |
| RNF20 | E3 ubiquitin-protein ligase BRE1A (BRE1-A) (hBRE1) (EC 2.3.2.27) (RING finger protein 20) (RING-type E3 ubiquitin transferase BRE1A) | 5 | UniProt   NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
|   CORUM:1165 | 1.02521027753e-05 | 0.666666666667 | RNF20 RNF40 | RNF20-RNF40-UbE2E1 complex |
|   WP:WP3878 | 0.000927197171072 | 0.666666666667 | RNF20 RNF40 | ATM signaling in development and disease |
|   GO:0033503 | 0.00842684400117 | 0.666666666667 | RNF20 RNF40 | HULC complex |
|   REAC:R-HSA-8866654 | 0.00973406489476 | 0.666666666667 | RNF20 RNF40 | E3 ubiquitin ligases ubiquitinate target proteins |
|   REAC:R-HSA-8852135 | 0.0183561585619 | 0.666666666667 | RNF20 RNF40 | Protein ubiquitination |
|   GO:0031371 | 0.0393180950424 | 0.666666666667 | RNF20 RNF40 | ubiquitin conjugating enzyme complex |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
|  RNF40 |  RNF20 | 0.998 | 0.938           |          | bioplex3_HEK293     bioplex_WMM     bioplex3_WMM     youn_WMM     bioplex3_HCT116     WMM_only     |
|  IL36A |  RNF40 | 0.965 |            |          | bioplex3_HEK293     bioplex ()     bioplex_WMM     bioplex3_WMM     |
|  IL36A |  RNF20 | 0.964 |            |          | bioplex3_HEK293     bioplex ()     bioplex_WMM     bioplex3_WMM     |
Related Complexes
| Genename | Complexes |
|---|---|
| IL36A | huMAP3_02044.1 huMAP3_02812.1 huMAP3_11660.1 |
| RNF40 | huMAP3_02044.1 huMAP3_02812.1 |
| RNF20 | huMAP3_02044.1 huMAP3_02812.1 huMAP3_11392.1 |