hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_02823.1
Complex Portal: CPX-24570
Confidence: Extremely High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| WNT7B | Protein Wnt-7b | 5 | UniProt NCBI |
| WNT4 | Protein Wnt-4 | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| WP:WP4150 | 0.000238782367243 | 1.0 | WNT7B WNT4 | Wnt signaling in kidney disease |
| KEGG:05217 | 0.000241415996293 | 1.0 | WNT7B WNT4 | Basal cell carcinoma |
| REAC:R-HSA-3238698 | 0.000512628525639 | 1.0 | WNT7B WNT4 | WNT ligand biogenesis and trafficking |
| KEGG:04916 | 0.000553224670293 | 1.0 | WNT7B WNT4 | Melanogenesis |
| WP:WP4336 | 0.00114964558631 | 1.0 | WNT7B WNT4 | ncRNAs involved in Wnt signaling in hepatocellular carcinoma |
| KEGG:04550 | 0.00116074761854 | 1.0 | WNT7B WNT4 | Signaling pathways regulating pluripotency of stem cells |
| KEGG:04934 | 0.00125991513217 | 1.0 | WNT7B WNT4 | Cushing syndrome |
| KEGG:05224 | 0.00130072012548 | 1.0 | WNT7B WNT4 | Breast cancer |
| KEGG:05226 | 0.00138428094844 | 1.0 | WNT7B WNT4 | Gastric cancer |
| WP:WP4258 | 0.00144844277313 | 1.0 | WNT7B WNT4 | lncRNA in canonical Wnt signaling and colorectal cancer |
| KEGG:04390 | 0.001720800216 | 1.0 | WNT7B WNT4 | Hippo signaling pathway |
| KEGG:04150 | 0.00176843313648 | 1.0 | WNT7B WNT4 | mTOR signaling pathway |
| KEGG:04310 | 0.00181671633574 | 1.0 | WNT7B WNT4 | Wnt signaling pathway |
| WP:WP399 | 0.0018604594068 | 1.0 | WNT7B WNT4 | Wnt signaling pathway and pluripotency |
| KEGG:05225 | 0.00204203793228 | 1.0 | WNT7B WNT4 | Hepatocellular carcinoma |
| WP:WP3931 | 0.00210690324038 | 1.0 | WNT7B WNT4 | Embryonic stem cell pluripotency pathways |
| WP:WP428 | 0.0021494669422 | 1.0 | WNT7B WNT4 | Wnt signaling |
| WP:WP710 | 0.0021494669422 | 1.0 | WNT7B WNT4 | DNA damage response only ATM dependent |
| WP:WP4787 | 0.00219245628104 | 1.0 | WNT7B WNT4 | Osteoblast differentiation and related diseases |
| KEGG:05205 | 0.00267768543767 | 1.0 | WNT7B WNT4 | Proteoglycans in cancer |
| WP:WP4239 | 0.00368005765986 | 1.0 | WNT7B WNT4 | Epithelial to mesenchymal transition in colorectal cancer |
| WP:WP4262 | 0.00373624174627 | 1.0 | WNT7B WNT4 | Breast cancer pathway |
| REAC:R-HSA-373080 | 0.00389255927135 | 1.0 | WNT7B WNT4 | Class B/2 (Secretin family receptors) |
| KEGG:05165 | 0.00700203931066 | 1.0 | WNT7B WNT4 | Human papillomavirus infection |
| KEGG:05010 | 0.0093688914925 | 1.0 | WNT7B WNT4 | Alzheimer disease |
| WP:WP5124 | 0.01130704739 | 1.0 | WNT7B WNT4 | Alzheimer 39 s disease |
| WP:WP2059 | 0.01130704739 | 1.0 | WNT7B WNT4 | Alzheimer 39 s disease and miRNA effects |
| HP:0000776 | 0.0113495955576 | 1.0 | WNT7B WNT4 | Congenital diaphragmatic hernia |
| KEGG:05022 | 0.0138982457502 | 1.0 | WNT7B WNT4 | Pathways of neurodegeneration - multiple diseases |
| KEGG:05200 | 0.0161326036311 | 1.0 | WNT7B WNT4 | Pathways in cancer |
| HP:0000775 | 0.0172584936965 | 1.0 | WNT7B WNT4 | Abnormality of the diaphragm |
| HP:0002089 | 0.0224018665704 | 1.0 | WNT7B WNT4 | Pulmonary hypoplasia |
| WP:WP5087 | 0.0293715080819 | 1.0 | WNT7B WNT4 | Pleural mesothelioma |
| HP:0006703 | 0.0304535519464 | 1.0 | WNT7B WNT4 | Aplasia/Hypoplasia of the lungs |
| WP:WP4814 | 0.0435328773163 | 0.5 | WNT4 | Somatic sex determination |
| REAC:R-HSA-500792 | 0.0446089343011 | 1.0 | WNT7B WNT4 | GPCR ligand binding |
| HP:0032073 | 0.0499436884913 | 0.5 | WNT4 | Aplasia of the fallopian tube |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| WNT7B | WNT4 | 0.996 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM |
Related Complexes