hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_02836.1
Confidence: Extremely High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| PIGA | Phosphatidylinositol N-acetylglucosaminyltransferase subunit A (EC 2.4.1.198) (GlcNAc-PI synthesis protein) (Phosphatidylinositol-glycan biosynthesis class A protein) (PIG-A) | 5 | UniProt NCBI |
| PIGP | Phosphatidylinositol N-acetylglucosaminyltransferase subunit P (Down syndrome critical region protein 5) (Down syndrome critical region protein C) (Phosphatidylinositol-glycan biosynthesis class P protein) (PIG-P) | 5 | UniProt NCBI |
| IL18RAP | Interleukin-18 receptor accessory protein (IL-18 receptor accessory protein) (IL-18RAcP) (EC 3.2.2.6) (Accessory protein-like) (AcPL) (CD218 antigen-like family member B) (CDw218b) (IL-1R accessory protein-like) (IL-1RAcPL) (Interleukin-1 receptor 7) (IL-1R-7) (IL-1R7) (Interleukin-18 receptor accessory protein-like) (Interleukin-18 receptor beta) (IL-18R-beta) (IL-18Rbeta) (CD antigen CD218b) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| KEGG:00563 | 0.0001601688991 | 0.666666666667 | PIGA PIGP | Glycosylphosphatidylinositol (GPI)-anchor biosynthesis |
| REAC:R-HSA-162710 | 0.000449812862905 | 0.666666666667 | PIGA PIGP | Synthesis of glycosylphosphatidylinositol (GPI) |
| GO:0017176 | 0.00421361424067 | 0.666666666667 | PIGA PIGP | phosphatidylinositol N-acetylglucosaminyltransferase activity |
| GO:0000506 | 0.0140440992017 | 0.666666666667 | PIGA PIGP | glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex |
| REAC:R-HSA-163125 | 0.0141416283812 | 0.666666666667 | PIGA PIGP | Post-translational modification: synthesis of GPI-anchored proteins |
| HP:0010841 | 0.023094623718 | 0.666666666667 | PIGA PIGP | Multifocal epileptiform discharges |
| HP:0020221 | 0.0262448238426 | 0.666666666667 | PIGA PIGP | Clonic seizure |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| PIGA | PIGP | 0.97 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | |
| PIGA | IL18RAP | 0.969 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM |
Related Complexes