hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_02851.1
Complex Portal: CPX-15428
Confidence: Extremely High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| ZNF22 | Zinc finger protein 22 (Zinc finger protein KOX15) (Zinc finger protein Krox-26) | 4 | UniProt NCBI |
| BRD1 | Bromodomain-containing protein 1 (BR140-like protein) (Bromodomain and PHD finger-containing protein 2) | 5 | UniProt NCBI |
| RPS26 | Small ribosomal subunit protein eS26 (40S ribosomal protein S26) | 5 | UniProt NCBI |
| RPL24 | Large ribosomal subunit protein eL24 (60S ribosomal protein L24) (60S ribosomal protein L30) | 5 | UniProt NCBI |
| H1-0 | Histone H1.0 (Histone H1') (Histone H1(0)) [Cleaved into: Histone H1.0, N-terminally processed] | 5 | UniProt NCBI |
| H2BC11 | Histone H2B type 1-J (Histone H2B.1) (Histone H2B.r) (H2B/r) | 5 | UniProt NCBI |
| DNAJC9 | DnaJ homolog subfamily C member 9 (HDJC9) (DnaJ protein SB73) | 5 | UniProt NCBI |
| RPL23A | Large ribosomal subunit protein uL23 (60S ribosomal protein L23a) | 5 | UniProt NCBI |
| GRSF1 | G-rich sequence factor 1 (GRSF-1) | 5 | UniProt NCBI |
| RSL24D1 | Probable ribosome biogenesis protein RLP24 (Ribosomal L24 domain-containing protein 1) (Ribosomal protein L24-like) | 4 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-192823 | 3.58057615283e-05 | 0.444444444444 | RPS26 GRSF1 RPL24 RPL23A | Viral mRNA Translation |
| KEGG:03010 | 3.67831026896e-05 | 0.444444444444 | RPS26 RSL24D1 RPL24 RPL23A | Ribosome |
| REAC:R-HSA-168273 | 0.000177791163859 | 0.444444444444 | RPS26 GRSF1 RPL24 RPL23A | Influenza Viral RNA Transcription and Replication |
| KEGG:05171 | 0.00021375047254 | 0.444444444444 | RPS26 RSL24D1 RPL24 RPL23A | Coronavirus disease - COVID-19 |
| REAC:R-HSA-168255 | 0.000289842292638 | 0.444444444444 | RPS26 GRSF1 RPL24 RPL23A | Influenza Infection |
| CORUM:306 | 0.000797811202177 | 0.333333333333 | RPS26 RPL24 RPL23A | Ribosome, cytoplasmic |
| WP:WP477 | 0.00152175784975 | 0.333333333333 | RPS26 RPL24 RPL23A | Cytoplasmic ribosomal proteins |
| REAC:R-HSA-156902 | 0.00409047033728 | 0.333333333333 | RPS26 RPL24 RPL23A | Peptide chain elongation |
| REAC:R-HSA-72764 | 0.00452422603622 | 0.333333333333 | RPS26 RPL24 RPL23A | Eukaryotic Translation Termination |
| REAC:R-HSA-2408557 | 0.00452422603622 | 0.333333333333 | RPS26 RPL24 RPL23A | Selenocysteine synthesis |
| REAC:R-HSA-156842 | 0.00467528343252 | 0.333333333333 | RPS26 RPL24 RPL23A | Eukaryotic Translation Elongation |
| REAC:R-HSA-975956 | 0.0049873114417 | 0.333333333333 | RPS26 RPL24 RPL23A | Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) |
| REAC:R-HSA-72689 | 0.00600515130063 | 0.333333333333 | RPS26 RPL24 RPL23A | Formation of a pool of free 40S subunits |
| REAC:R-HSA-9633012 | 0.00600515130063 | 0.333333333333 | RPS26 RPL24 RPL23A | Response of EIF2AK4 (GCN2) to amino acid deficiency |
| REAC:R-HSA-9824446 | 0.00644900522555 | 0.555555555556 | RPS26 GRSF1 RPL23A RPL24 H2BC11 | Viral Infection Pathways |
| REAC:R-HSA-2262752 | 0.00738791222428 | 0.555555555556 | RPS26 RPL23A RPL24 H2BC11 H1-0 | Cellular responses to stress |
| REAC:R-HSA-8953897 | 0.0077407268337 | 0.555555555556 | RPS26 RPL23A RPL24 H2BC11 H1-0 | Cellular responses to stimuli |
| REAC:R-HSA-1799339 | 0.00799030388712 | 0.333333333333 | RPS26 RPL24 RPL23A | SRP-dependent cotranslational protein targeting to membrane |
| REAC:R-HSA-156827 | 0.00799030388712 | 0.333333333333 | RPS26 RPL24 RPL23A | L13a-mediated translational silencing of Ceruloplasmin expression |
| REAC:R-HSA-72706 | 0.00820971843063 | 0.333333333333 | RPS26 RPL24 RPL23A | GTP hydrolysis and joining of the 60S ribosomal subunit |
| REAC:R-HSA-2408522 | 0.00820971843063 | 0.333333333333 | RPS26 RPL24 RPL23A | Selenoamino acid metabolism |
| REAC:R-HSA-975957 | 0.00889169623462 | 0.333333333333 | RPS26 RPL24 RPL23A | Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) |
| REAC:R-HSA-927802 | 0.00889169623462 | 0.333333333333 | RPS26 RPL24 RPL23A | Nonsense-Mediated Decay (NMD) |
| REAC:R-HSA-72737 | 0.00985761897121 | 0.333333333333 | RPS26 RPL24 RPL23A | Cap-dependent Translation Initiation |
| REAC:R-HSA-72613 | 0.00985761897121 | 0.333333333333 | RPS26 RPL24 RPL23A | Eukaryotic Translation Initiation |
| REAC:R-HSA-5663205 | 0.0174507834687 | 0.555555555556 | RPS26 GRSF1 RPL23A RPL24 H2BC11 | Infectious disease |
| REAC:R-HSA-9711097 | 0.0213823347316 | 0.333333333333 | RPS26 RPL24 RPL23A | Cellular response to starvation |
| CORUM:308 | 0.0232598668614 | 0.222222222222 | RPL23A RPL24 | 60S ribosomal subunit, cytoplasmic |
| REAC:R-HSA-9010553 | 0.0272414852694 | 0.333333333333 | RPS26 RPL24 RPL23A | Regulation of expression of SLITs and ROBOs |
| REAC:R-HSA-6791226 | 0.0346303469412 | 0.333333333333 | RPS26 RPL24 RPL23A | Major pathway of rRNA processing in the nucleolus and cytosol |
| REAC:R-HSA-8868773 | 0.0406385856249 | 0.333333333333 | RPS26 RPL24 RPL23A | rRNA processing in the nucleus and cytosol |
| REAC:R-HSA-72312 | 0.0472897657656 | 0.333333333333 | RPS26 RPL24 RPL23A | rRNA processing |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| RPL24 | RPL23A | 1.0 | 0.996 | hein_WMM bioplex3_HEK293 bioplex_WMM bioplex3_WMM boldt Malo bioplex3_HCT116 gupta_WMM fraction boldt_WMM treiber_WMM | |
| DNAJC9 | RPL23A | 0.997 | 0.138 | hein_WMM bioplex3_HEK293 bioplex_WMM bioplex3_WMM bioplex3_HCT116 gupta_WMM fraction treiber_WMM | |
| RPS26 | RPL23A | 0.996 | 0.996 | bioplex3_HEK293 bioplex_WMM bioplex3_WMM boldt bioplex3_HCT116 WMM_only | |
| RPL23A | GRSF1 | 0.985 | 0.842 | bioplex3_HEK293 bioplex_WMM bioplex3_WMM bioplex3_HCT116 treiber_WMM WMM_only | |
| RPL23A | RSL24D1 | 0.983 | 0.774 | bioplex3_HEK293 bioplex_WMM bioplex3_WMM bioplex3_HCT116 treiber_WMM WMM_only | |
| H2BC11 | RPL23A | 0.972 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | ||
| H1-0 | RPL23A | 0.971 | 0.154 | bioplex3_HEK293 bioplex_WMM bioplex3_WMM bioplex3_HCT116 gupta_WMM treiber_WMM WMM_only | |
| ZNF22 | RPL23A | 0.969 | 0.42 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | |
| BRD1 | RPL23A | 0.96 | 0.316 | hein_WMM bioplex3_HEK293 bioplex3_WMM WMM_only | |
| H2BC11 | RSL24D1 | 0.955 | bioplex_WMM bioplex3_WMM WMM_only | ||
| ZNF22 | RPS26 | 0.955 | 0.126 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | |
| ZNF22 | H2BC11 | 0.947 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | ||
| RPS26 | H2BC11 | 0.943 | bioplex_WMM bioplex3_WMM WMM_only | ||
| ZNF22 | RSL24D1 | 0.927 | 0.082 | bioplex_WMM bioplex3_WMM WMM_only | |
| ZNF22 | H1-0 | 0.914 | 0.122 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | |
| RPS26 | RSL24D1 | 0.908 | 0.436 | bioplex_WMM bioplex3_WMM WMM_only | |
| RPS26 | GRSF1 | 0.908 | 0.656 | bioplex_WMM bioplex3_WMM WMM_only | |
| RPS26 | H1-0 | 0.897 | 0.094 | bioplex_WMM bioplex3_WMM WMM_only | |
| RPS26 | RPL24 | 0.894 | 0.996 | bioplex_WMM bioplex3_WMM boldt WMM_only | |
| H1-0 | RSL24D1 | 0.88 | 0.104 | bioplex_WMM bioplex3_WMM WMM_only treiber_WMM | |
| GRSF1 | RSL24D1 | 0.877 | 0.402 | bioplex_WMM bioplex3_WMM WMM_only treiber_WMM | |
| H2BC11 | GRSF1 | 0.869 | bioplex_WMM bioplex3_WMM WMM_only | ||
| RPL24 | DNAJC9 | 0.847 | 0.08 | hein_WMM bioplex_WMM bioplex3_WMM gupta_WMM WMM_only treiber_WMM | |
| H1-0 | H2BC11 | 0.819 | bioplex_WMM bioplex3_WMM WMM_only | ||
| RPL24 | RSL24D1 | 0.794 | 0.644 | bioplex_WMM bioplex3_WMM WMM_only treiber_WMM | |
| ZNF22 | GRSF1 | 0.746 | 0.07 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | |
| H2BC11 | DNAJC9 | 0.744 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM boldt boldt_WMM | ||
| ZNF22 | DNAJC9 | 0.725 | 0.06 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | |
| H1-0 | GRSF1 | 0.692 | 0.074 | bioplex_WMM bioplex3_WMM youn_WMM fraction treiber_WMM | |
| RPL24 | GRSF1 | 0.689 | 0.648 | bioplex_WMM bioplex3_WMM WMM_only treiber_WMM | |
| RPL24 | H2BC11 | 0.649 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | ||
| BRD1 | RPL24 | 0.517 | 0.205333333333 | hein_WMM bioplex3_HEK293 bioplex3_HCT116 WMM_only | |
| RPL24 | H1-0 | 0.509 | 0.08 | bioplex_WMM bioplex3_WMM gupta_WMM fraction treiber_WMM | |
| ZNF22 | RPL24 | 0.481 | 0.208 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | |
| RPS26 | DNAJC9 | 0.417 | 0.104 | bioplex_WMM bioplex3_WMM boldt WMM_only | |
| H1-0 | DNAJC9 | 0.395 | 0.108 | bioplex_WMM bioplex3_WMM fraction treiber_WMM | |
| DNAJC9 | GRSF1 | 0.34 | 0.104 | bioplex_WMM bioplex3_WMM youn_WMM WMM_only treiber_WMM | |
| DNAJC9 | RSL24D1 | 0.309 | 0.034 | bioplex_WMM bioplex3_WMM WMM_only treiber_WMM | |
| BRD1 | DNAJC9 | 0.172 | 0.248 | hein_WMM bioplex3_HEK293 bioplex3_WMM bioplex3_HCT116 WMM_only | |
| BRD1 | H1-0 | 0.074 | 0.216 | bioplex3_HEK293 bioplex3_WMM WMM_only | |
| BRD1 | H2BC11 | 0.019 | bioplex3_HEK293 bioplex3_WMM WMM_only | ||
| BRD1 | GRSF1 | 0.017 | 0.1795 | bioplex3_HEK293 WMM_only | |
| BRD1 | RPS26 | 0.008 | 0.17 | bioplex3_HEK293 bioplex3_HCT116 WMM_only |
Related Complexes
| Genename | Complexes |
|---|---|
| ZNF22 | huMAP3_02851.1 |
| BRD1 | huMAP3_02851.1 huMAP3_03602.1 huMAP3_08842.1 |
| RPS26 | huMAP3_02851.1 |
| RPL24 | huMAP3_02851.1 |
| H1-0 | huMAP3_02851.1 |
| H2BC11 | huMAP3_02851.1 |
| DNAJC9 | huMAP3_02851.1 |
| RPL23A | huMAP3_02851.1 |
| GRSF1 | huMAP3_02851.1 |
| RSL24D1 | huMAP3_02851.1 |