hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_02870.1
Complex Portal: CPX-24003
Confidence: Extremely High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| ARHGAP42 | Rho GTPase-activating protein 42 (Rho GTPase-activating protein 10-like) (Rho-type GTPase-activating protein 42) | 4 | UniProt NCBI |
| GCH1 | GTP cyclohydrolase 1 (EC 3.5.4.16) (GTP cyclohydrolase I) (GTP-CH-I) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| HP:0040417 | 0.0499436884913 | 0.5 | GCH1 | Decreased urinary biopterin level |
| HP:0040420 | 0.0499436884913 | 0.5 | GCH1 | Decreased urinary neopterin level |
| HP:0500214 | 0.0499436884913 | 0.5 | GCH1 | Abnormal CSF aromatic amino acid concentration |
| HP:0500215 | 0.0499436884913 | 0.5 | GCH1 | Abnormal CSF phenylalanine concentration |
| HP:0500223 | 0.0499436884913 | 0.5 | GCH1 | Increased CSF phenylalanine concentration |
| HP:6000120 | 0.0499436884913 | 0.5 | GCH1 | Elevated urinary sulfatide level |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| ARHGAP42 | GCH1 | 0.984 | bioplex3_HEK293 bioplex3_WMM WMM_only |
Related Complexes
| Genename | Complexes |
|---|---|
| ARHGAP42 | huMAP3_00408.1 huMAP3_02870.1 huMAP3_06367.1 huMAP3_08723.1 huMAP3_13324.1 huMAP3_14476.1 |
| GCH1 | huMAP3_00408.1 huMAP3_02870.1 huMAP3_05446.1 huMAP3_08723.1 huMAP3_13715.1 huMAP3_14942.1 |