hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_02890.1
Complex Portal: CPX-14213
Confidence: Extremely High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| GABRE | Gamma-aminobutyric acid receptor subunit epsilon (GABA(A) receptor subunit epsilon) | 5 | UniProt NCBI |
| HMBS | Porphobilinogen deaminase (PBG-D) (EC 2.5.1.61) (Hydroxymethylbilane synthase) (HMBS) (Pre-uroporphyrinogen synthase) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| WP:WP5169 | 0.049750157242 | 0.5 | HMBS | Hemesynthesis defects and porphyrias |
| WP:WP561 | 0.049750157242 | 0.5 | HMBS | Heme biosynthesis |
| HP:4000199 | 0.0499436884913 | 0.5 | HMBS | Reduced erythrocyte porphobilinogen deaminase activity |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| GABRE | HMBS | 0.974 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM |
Related Complexes
| Genename | Complexes |
|---|---|
| GABRE | huMAP3_02890.1 huMAP3_06275.1 huMAP3_13961.1 huMAP3_15126.1 |
| HMBS | huMAP3_02890.1 huMAP3_13961.1 |