hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_02903.1
Confidence: Extremely High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| HAUS7 | HAUS augmin-like complex subunit 7 (26S proteasome-associated UCH37-interacting protein 1) (UCHL5-interacting protein) (X-linked protein STS1769) | 5 | UniProt NCBI |
| HAUS8 | HAUS augmin-like complex subunit 8 (HEC1/NDC80-interacting centrosome-associated protein 1) (Sarcoma antigen NY-SAR-48) | 5 | UniProt NCBI |
| HAUS3 | HAUS augmin-like complex subunit 3 | 5 | UniProt NCBI |
| HAUS2 | HAUS augmin-like complex subunit 2 (Centrosomal protein of 27 kDa) (Cep27) | 5 | UniProt NCBI |
| HAUS6 | HAUS augmin-like complex subunit 6 | 5 | UniProt NCBI |
| RNF10 | E3 ubiquitin-protein ligase RNF10 (EC 2.3.2.27) (RING finger protein 10) | 5 | UniProt NCBI |
| HAUS4 | HAUS augmin-like complex subunit 4 | 5 | UniProt NCBI |
| HAUS5 | HAUS augmin-like complex subunit 5 | 5 | UniProt NCBI |
| HAUS1 | HAUS augmin-like complex subunit 1 (Coiled-coil domain-containing protein 5) (Enhancer of invasion-cluster) (HEI-C) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| GO:0070652 | 8.73322522913e-24 | 0.888888888889 | HAUS1 HAUS3 HAUS6 HAUS8 HAUS4 HAUS5 HAUS2 HAUS7 | HAUS complex |
| GO:1990498 | 2.62162997257e-20 | 0.888888888889 | HAUS1 HAUS3 HAUS6 HAUS8 HAUS4 HAUS5 HAUS2 HAUS7 | mitotic spindle microtubule |
| GO:0010968 | 2.12188429723e-19 | 0.888888888889 | HAUS1 HAUS3 HAUS6 HAUS8 HAUS4 HAUS5 HAUS2 HAUS7 | regulation of microtubule nucleation |
| CORUM:6435 | 5.04259335805e-19 | 0.666666666667 | HAUS1 HAUS2 HAUS8 HAUS7 HAUS5 HAUS6 | HAUS augmin-like complex |
| REAC:R-HSA-380259 | 2.36885635229e-16 | 0.888888888889 | HAUS1 HAUS3 HAUS6 HAUS8 HAUS4 HAUS5 HAUS2 HAUS7 | Loss of Nlp from mitotic centrosomes |
| REAC:R-HSA-380284 | 2.36885635229e-16 | 0.888888888889 | HAUS1 HAUS3 HAUS6 HAUS8 HAUS4 HAUS5 HAUS2 HAUS7 | Loss of proteins required for interphase microtubule organization from the centrosome |
| REAC:R-HSA-8854518 | 3.44793334624e-16 | 0.888888888889 | HAUS1 HAUS3 HAUS6 HAUS8 HAUS4 HAUS5 HAUS2 HAUS7 | AURKA Activation by TPX2 |
| REAC:R-HSA-380287 | 9.66325302868e-16 | 0.888888888889 | HAUS1 HAUS3 HAUS6 HAUS8 HAUS4 HAUS5 HAUS2 HAUS7 | Centrosome maturation |
| REAC:R-HSA-380270 | 9.66325302868e-16 | 0.888888888889 | HAUS1 HAUS3 HAUS6 HAUS8 HAUS4 HAUS5 HAUS2 HAUS7 | Recruitment of mitotic centrosome proteins and complexes |
| GO:0007020 | 1.54442160964e-15 | 0.888888888889 | HAUS1 HAUS3 HAUS6 HAUS8 HAUS4 HAUS5 HAUS2 HAUS7 | microtubule nucleation |
| REAC:R-HSA-2565942 | 1.62509209407e-15 | 0.888888888889 | HAUS1 HAUS3 HAUS6 HAUS8 HAUS4 HAUS5 HAUS2 HAUS7 | Regulation of PLK1 Activity at G2/M Transition |
| REAC:R-HSA-380320 | 3.19233401146e-15 | 0.888888888889 | HAUS1 HAUS3 HAUS6 HAUS8 HAUS4 HAUS5 HAUS2 HAUS7 | Recruitment of NuMA to mitotic centrosomes |
| REAC:R-HSA-5620912 | 4.19338269766e-15 | 0.888888888889 | HAUS1 HAUS3 HAUS6 HAUS8 HAUS4 HAUS5 HAUS2 HAUS7 | Anchoring of the basal body to the plasma membrane |
| GO:0031113 | 6.55448800864e-15 | 0.888888888889 | HAUS1 HAUS3 HAUS6 HAUS8 HAUS4 HAUS5 HAUS2 HAUS7 | regulation of microtubule polymerization |
| GO:0005876 | 1.31093941811e-13 | 0.888888888889 | HAUS1 HAUS3 HAUS6 HAUS8 HAUS4 HAUS5 HAUS2 HAUS7 | spindle microtubule |
| GO:0031110 | 2.03894638905e-13 | 0.888888888889 | HAUS1 HAUS3 HAUS6 HAUS8 HAUS4 HAUS5 HAUS2 HAUS7 | regulation of microtubule polymerization or depolymerization |
| GO:0046785 | 2.79649834765e-13 | 0.888888888889 | HAUS1 HAUS3 HAUS6 HAUS8 HAUS4 HAUS5 HAUS2 HAUS7 | microtubule polymerization |
| REAC:R-HSA-69275 | 1.42248546324e-12 | 0.888888888889 | HAUS1 HAUS3 HAUS6 HAUS8 HAUS4 HAUS5 HAUS2 HAUS7 | G2/M Transition |
| REAC:R-HSA-5617833 | 1.42248546324e-12 | 0.888888888889 | HAUS1 HAUS3 HAUS6 HAUS8 HAUS4 HAUS5 HAUS2 HAUS7 | Cilium Assembly |
| REAC:R-HSA-453274 | 1.54974012842e-12 | 0.888888888889 | HAUS1 HAUS3 HAUS6 HAUS8 HAUS4 HAUS5 HAUS2 HAUS7 | Mitotic G2-G2/M phases |
| REAC:R-HSA-68877 | 1.8344367333e-12 | 0.888888888889 | HAUS1 HAUS3 HAUS6 HAUS8 HAUS4 HAUS5 HAUS2 HAUS7 | Mitotic Prometaphase |
| GO:0051225 | 1.90419808573e-12 | 0.888888888889 | HAUS1 HAUS3 HAUS6 HAUS8 HAUS4 HAUS5 HAUS2 HAUS7 | spindle assembly |
| GO:0031109 | 4.12628985472e-12 | 0.888888888889 | HAUS1 HAUS3 HAUS6 HAUS8 HAUS4 HAUS5 HAUS2 HAUS7 | microtubule polymerization or depolymerization |
| GO:0007098 | 6.34578326878e-12 | 0.888888888889 | HAUS1 HAUS3 HAUS6 HAUS8 HAUS4 HAUS5 HAUS2 HAUS7 | centrosome cycle |
| GO:0005875 | 8.93117431221e-12 | 0.888888888889 | HAUS1 HAUS3 HAUS6 HAUS8 HAUS4 HAUS5 HAUS2 HAUS7 | microtubule associated complex |
| GO:0070507 | 1.40790046698e-11 | 0.888888888889 | HAUS1 HAUS3 HAUS6 HAUS8 HAUS4 HAUS5 HAUS2 HAUS7 | regulation of microtubule cytoskeleton organization |
| GO:0032271 | 1.69805645728e-11 | 0.888888888889 | HAUS1 HAUS3 HAUS6 HAUS8 HAUS4 HAUS5 HAUS2 HAUS7 | regulation of protein polymerization |
| GO:0031023 | 1.80575882964e-11 | 0.888888888889 | HAUS1 HAUS3 HAUS6 HAUS8 HAUS4 HAUS5 HAUS2 HAUS7 | microtubule organizing center organization |
| REAC:R-HSA-1852241 | 2.9805216679e-11 | 0.888888888889 | HAUS1 HAUS3 HAUS6 HAUS8 HAUS4 HAUS5 HAUS2 HAUS7 | Organelle biogenesis and maintenance |
| GO:0072686 | 7.33011691397e-11 | 0.888888888889 | HAUS1 HAUS3 HAUS6 HAUS8 HAUS4 HAUS5 HAUS2 HAUS7 | mitotic spindle |
| GO:0007051 | 8.53957008922e-11 | 0.888888888889 | HAUS1 HAUS3 HAUS6 HAUS8 HAUS4 HAUS5 HAUS2 HAUS7 | spindle organization |
| GO:0032886 | 4.03512211403e-10 | 0.888888888889 | HAUS1 HAUS3 HAUS6 HAUS8 HAUS4 HAUS5 HAUS2 HAUS7 | regulation of microtubule-based process |
| REAC:R-HSA-68886 | 4.6913619393e-10 | 0.888888888889 | HAUS1 HAUS3 HAUS6 HAUS8 HAUS4 HAUS5 HAUS2 HAUS7 | M Phase |
| GO:0051258 | 4.75569746963e-10 | 0.888888888889 | HAUS1 HAUS3 HAUS6 HAUS8 HAUS4 HAUS5 HAUS2 HAUS7 | protein polymerization |
| GO:1902903 | 5.26123588988e-09 | 0.888888888889 | HAUS1 HAUS3 HAUS6 HAUS8 HAUS4 HAUS5 HAUS2 HAUS7 | regulation of supramolecular fiber organization |
| REAC:R-HSA-69278 | 5.52227860343e-09 | 0.888888888889 | HAUS1 HAUS3 HAUS6 HAUS8 HAUS4 HAUS5 HAUS2 HAUS7 | Cell Cycle, Mitotic |
| GO:0005874 | 5.75503798119e-09 | 0.888888888889 | HAUS1 HAUS3 HAUS6 HAUS8 HAUS4 HAUS5 HAUS2 HAUS7 | microtubule |
| GO:0043254 | 9.39508113061e-09 | 0.888888888889 | HAUS1 HAUS3 HAUS6 HAUS8 HAUS4 HAUS5 HAUS2 HAUS7 | regulation of protein-containing complex assembly |
| GO:0005819 | 1.34049798491e-08 | 0.888888888889 | HAUS1 HAUS3 HAUS6 HAUS8 HAUS4 HAUS5 HAUS2 HAUS7 | spindle |
| GO:0140694 | 1.65556125682e-08 | 0.888888888889 | HAUS1 HAUS3 HAUS6 HAUS8 HAUS4 HAUS5 HAUS2 HAUS7 | non-membrane-bounded organelle assembly |
| GO:0007059 | 2.30635375587e-08 | 0.888888888889 | HAUS1 HAUS3 HAUS6 HAUS8 HAUS4 HAUS5 HAUS2 HAUS7 | chromosome segregation |
| REAC:R-HSA-1640170 | 2.90076944325e-08 | 0.888888888889 | HAUS1 HAUS3 HAUS6 HAUS8 HAUS4 HAUS5 HAUS2 HAUS7 | Cell Cycle |
| GO:0051493 | 8.19055651869e-08 | 0.888888888889 | HAUS1 HAUS3 HAUS6 HAUS8 HAUS4 HAUS5 HAUS2 HAUS7 | regulation of cytoskeleton organization |
| GO:0099513 | 1.87572566404e-07 | 0.888888888889 | HAUS1 HAUS3 HAUS6 HAUS8 HAUS4 HAUS5 HAUS2 HAUS7 | polymeric cytoskeletal fiber |
| GO:0000226 | 6.92830366442e-07 | 0.888888888889 | HAUS1 HAUS3 HAUS6 HAUS8 HAUS4 HAUS5 HAUS2 HAUS7 | microtubule cytoskeleton organization |
| GO:0005813 | 1.48170310221e-06 | 0.888888888889 | HAUS1 HAUS3 HAUS6 HAUS8 HAUS4 HAUS5 HAUS2 HAUS7 | centrosome |
| GO:0099512 | 1.84420110638e-06 | 0.888888888889 | HAUS1 HAUS3 HAUS6 HAUS8 HAUS4 HAUS5 HAUS2 HAUS7 | supramolecular fiber |
| GO:0099081 | 2.03836294509e-06 | 0.888888888889 | HAUS1 HAUS3 HAUS6 HAUS8 HAUS4 HAUS5 HAUS2 HAUS7 | supramolecular polymer |
| GO:0097435 | 3.57637043496e-06 | 0.888888888889 | HAUS1 HAUS3 HAUS6 HAUS8 HAUS4 HAUS5 HAUS2 HAUS7 | supramolecular fiber organization |
| GO:0005815 | 5.7521683782e-06 | 0.888888888889 | HAUS1 HAUS3 HAUS6 HAUS8 HAUS4 HAUS5 HAUS2 HAUS7 | microtubule organizing center |
| GO:0044087 | 8.90044257461e-06 | 0.888888888889 | HAUS1 HAUS3 HAUS6 HAUS8 HAUS4 HAUS5 HAUS2 HAUS7 | regulation of cellular component biogenesis |
| GO:0007017 | 1.07256914784e-05 | 0.888888888889 | HAUS1 HAUS3 HAUS6 HAUS8 HAUS4 HAUS5 HAUS2 HAUS7 | microtubule-based process |
| GO:0070925 | 1.66051672455e-05 | 0.888888888889 | HAUS1 HAUS3 HAUS6 HAUS8 HAUS4 HAUS5 HAUS2 HAUS7 | organelle assembly |
| GO:0099080 | 6.64269494283e-05 | 0.888888888889 | HAUS1 HAUS3 HAUS6 HAUS8 HAUS4 HAUS5 HAUS2 HAUS7 | supramolecular complex |
| GO:0033043 | 8.3965968302e-05 | 0.888888888889 | HAUS1 HAUS3 HAUS6 HAUS8 HAUS4 HAUS5 HAUS2 HAUS7 | regulation of organelle organization |
| GO:0022402 | 0.0001684779506 | 0.888888888889 | HAUS1 HAUS3 HAUS6 HAUS8 HAUS4 HAUS5 HAUS2 HAUS7 | cell cycle process |
| GO:0015630 | 0.000221054905678 | 0.888888888889 | HAUS1 HAUS3 HAUS6 HAUS8 HAUS4 HAUS5 HAUS2 HAUS7 | microtubule cytoskeleton |
| GO:0007010 | 0.000428673884053 | 0.888888888889 | HAUS1 HAUS3 HAUS6 HAUS8 HAUS4 HAUS5 HAUS2 HAUS7 | cytoskeleton organization |
| GO:0065003 | 0.000768691204562 | 0.888888888889 | HAUS1 HAUS3 HAUS6 HAUS8 HAUS4 HAUS5 HAUS2 HAUS7 | protein-containing complex assembly |
| GO:0007049 | 0.00121218210792 | 0.888888888889 | HAUS1 HAUS3 HAUS6 HAUS8 HAUS4 HAUS5 HAUS2 HAUS7 | cell cycle |
| GO:0005856 | 0.00564626210456 | 0.888888888889 | HAUS1 HAUS3 HAUS6 HAUS8 HAUS4 HAUS5 HAUS2 HAUS7 | cytoskeleton |
| GO:0043933 | 0.0109403276913 | 0.888888888889 | HAUS1 HAUS3 HAUS6 HAUS8 HAUS4 HAUS5 HAUS2 HAUS7 | protein-containing complex organization |
| GO:0051128 | 0.0132700478942 | 0.888888888889 | HAUS1 HAUS3 HAUS6 HAUS8 HAUS4 HAUS5 HAUS2 HAUS7 | regulation of cellular component organization |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| HAUS7 | HAUS8 | 1.0 | 0.35 | hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM bioplex3_HCT116 gupta_WMM |
| HAUS7 | HAUS4 | 1.0 | 0.274 | hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM hein () bioplex3_HCT116 gupta_WMM |
| HAUS7 | HAUS5 | 1.0 | 0.332 | hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM bioplex3_HCT116 gupta_WMM |
| HAUS7 | HAUS3 | 1.0 | 0.222 | hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM bioplex3_HCT116 gupta_WMM |
| HAUS7 | HAUS1 | 1.0 | 0.238 | hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM hein () bioplex3_HCT116 gupta_WMM |
| HAUS7 | HAUS6 | 1.0 | 0.208 | hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM bioplex3_HCT116 gupta_WMM |
| HAUS7 | HAUS2 | 1.0 | 0.686 | hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM hein () bioplex3_HCT116 gupta_WMM |
| HAUS4 | HAUS5 | 1.0 | 0.392 | hein_WMM bioplex3_HEK293 bioplex_WMM bioplex3_WMM youn_WMM hein () gupta_WMM |
| HAUS6 | HAUS5 | 1.0 | 0.122 | hein_WMM bioplex3_HEK293 bioplex_WMM bioplex3_WMM youn_WMM gupta_WMM WMM_only |
| HAUS2 | HAUS5 | 0.999 | 0.348 | hein_WMM bioplex3_HEK293 bioplex_WMM bioplex3_WMM youn_WMM hein () gupta_WMM |
| HAUS3 | HAUS5 | 0.999 | 0.188 | hein_WMM bioplex3_HEK293 bioplex_WMM bioplex3_WMM youn_WMM gupta_WMM WMM_only |
| HAUS4 | HAUS1 | 0.999 | 0.33 | hein_WMM bioplex_WMM bioplex3_WMM boldt youn_WMM hein () gupta_WMM boldt_WMM |
| HAUS3 | HAUS4 | 0.999 | 0.352 | hein_WMM bioplex_WMM bioplex3_WMM youn_WMM hein () gupta_WMM |
| HAUS8 | HAUS2 | 0.999 | 0.324 | hein_WMM bioplex_WMM bioplex3_WMM youn_WMM hein () gupta_WMM |
| HAUS3 | HAUS2 | 0.999 | 0.45 | hein_WMM bioplex_WMM bioplex3_WMM youn_WMM hein () gupta_WMM |
| HAUS2 | HAUS6 | 0.998 | 0.338 | hein_WMM bioplex_WMM bioplex3_WMM youn_WMM hein () gupta_WMM |
| HAUS8 | HAUS4 | 0.998 | 0.364 | hein_WMM bioplex_WMM bioplex3_WMM youn_WMM hein () gupta_WMM |
| HAUS2 | HAUS1 | 0.998 | 0.284 | hein_WMM bioplex_WMM bioplex3_WMM youn_WMM hein () gupta_WMM |
| HAUS8 | HAUS6 | 0.998 | 0.374 | hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM boldt youn_WMM gupta_WMM boldt_WMM |
| HAUS3 | HAUS1 | 0.998 | 0.12 | hein_WMM bioplex_WMM bioplex3_WMM youn_WMM hein () gupta_WMM |
| HAUS2 | HAUS4 | 0.998 | 0.474 | hein_WMM bioplex_WMM bioplex3_WMM youn_WMM hein () gupta_WMM |
| HAUS8 | HAUS5 | 0.997 | 0.268 | hein_WMM bioplex3_HEK293 bioplex_WMM bioplex3_WMM youn_WMM gupta_WMM WMM_only |
| HAUS6 | HAUS4 | 0.996 | 0.244 | hein_WMM bioplex_WMM bioplex3_WMM youn_WMM hein () gupta_WMM |
| HAUS3 | HAUS6 | 0.995 | 0.12 | hein_WMM bioplex_WMM bioplex3_WMM youn_WMM gupta_WMM WMM_only |
| HAUS6 | HAUS1 | 0.995 | 0.114 | hein_WMM bioplex_WMM bioplex3_WMM youn_WMM hein () gupta_WMM |
| HAUS8 | HAUS3 | 0.993 | 0.288 | hein_WMM bioplex_WMM bioplex3_WMM youn_WMM gupta_WMM WMM_only |
| HAUS8 | HAUS1 | 0.99 | 0.292 | hein_WMM bioplex_WMM bioplex3_WMM youn_WMM hein () gupta_WMM |
| HAUS3 | RNF10 | 0.988 | 0.104 | bioplex3_HEK293 bioplex3_WMM youn_WMM bioplex3_HCT116 WMM_only |
| HAUS5 | HAUS1 | 0.987 | 0.35 | hein_WMM bioplex3_HEK293 bioplex_WMM bioplex3_WMM youn_WMM hein () gupta_WMM |
| HAUS8 | RNF10 | 0.953 | 0.26 | bioplex3_HEK293 bioplex3_WMM youn_WMM bioplex3_HCT116 WMM_only |
| RNF10 | HAUS4 | 0.953 | 0.168 | bioplex3_HEK293 bioplex3_WMM youn_WMM bioplex3_HCT116 WMM_only |
| HAUS2 | RNF10 | 0.749 | 0.142 | bioplex3_HEK293 bioplex3_WMM youn_WMM WMM_only |
| RNF10 | HAUS1 | 0.615 | 0.204 | bioplex3_HEK293 bioplex3_WMM youn_WMM bioplex3_HCT116 WMM_only |
| RNF10 | HAUS5 | 0.581 | 0.134 | bioplex3_HEK293 bioplex3_WMM youn_WMM bioplex3_HCT116 WMM_only |
| HAUS6 | RNF10 | 0.406 | 0.122 | bioplex3_HEK293 bioplex3_WMM youn_WMM bioplex3_HCT116 WMM_only |
| HAUS7 | RNF10 | 0.224 | 0.216 | bioplex3_HEK293 bioplex3_WMM youn_WMM WMM_only |
Related Complexes
| Genename | Complexes |
|---|---|
| HAUS7 | huMAP3_02903.1 huMAP3_14852.1 |
| HAUS8 | huMAP3_02903.1 huMAP3_14852.1 |
| HAUS3 | huMAP3_02903.1 huMAP3_14852.1 |
| HAUS2 | huMAP3_02903.1 huMAP3_14852.1 |
| HAUS6 | huMAP3_02903.1 huMAP3_14852.1 |
| RNF10 | huMAP3_02903.1 huMAP3_08841.1 huMAP3_09037.1 huMAP3_12347.1 huMAP3_14144.1 huMAP3_14486.1 huMAP3_14852.1 |
| HAUS4 | huMAP3_02903.1 huMAP3_14852.1 |
| HAUS5 | huMAP3_02903.1 huMAP3_14852.1 |
| HAUS1 | huMAP3_02903.1 huMAP3_14852.1 |