hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_02926.1
Complex Portal: CPX-12175
Confidence: Extremely High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| STAT6 | Signal transducer and activator of transcription 6 (IL-4 Stat) | 5 | UniProt NCBI |
| NCOA1 | Nuclear receptor coactivator 1 (NCoA-1) (EC 2.3.1.48) (Class E basic helix-loop-helix protein 74) (bHLHe74) (Protein Hin-2) (RIP160) (Renal carcinoma antigen NY-REN-52) (Steroid receptor coactivator 1) (SRC-1) | 5 | UniProt NCBI |
| NR1I3 | Nuclear receptor subfamily 1 group I member 3 (Constitutive activator of retinoid response) (Constitutive active response) (Constitutive androstane receptor) (CAR) (Orphan nuclear receptor MB67) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| WP:WP2875 | 0.000312323469599 | 0.666666666667 | NCOA1 NR1I3 | Constitutive androstane receptor pathway |
| WP:WP236 | 0.0063930178049 | 0.666666666667 | NCOA1 STAT6 | Adipogenesis |
| WP:WP2882 | 0.0351361093338 | 0.666666666667 | NCOA1 NR1I3 | Nuclear receptors meta pathway |
| CORUM:1042 | 0.0499402709677 | 0.333333333333 | NCOA1 | SRA-SRC-1 ribonucleoprotein complex |
| CORUM:5461 | 0.0499402709677 | 0.333333333333 | NCOA1 | p50-p65 NF(kappa)B-SRC1 complex |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| STAT6 | NCOA1 | 0.976 | 0.114 | bioplex3_HEK293 bioplex3_WMM WMM_only | |
| NCOA1 | NR1I3 | 0.96 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM |
Related Complexes