hu.MAP 3.0: Complex View

Human Protein Complex Map

Complex: huMAP3_02933.1

Complex Portal: CPX-15728

Confidence: Extremely High

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Genename	Protein Name	Uniprot Annotation Score	Links
HSD3B1	3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 1 (3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type I) (3-beta-HSD I) (3-beta-hydroxy-5-ene steroid dehydrogenase) (3-beta-hydroxy-Delta(5)-steroid dehydrogenase) (EC 1.1.1.145) (3-beta-hydroxysteroid 3-dehydrogenase) (EC 1.1.1.270) (Delta-5-3-ketosteroid isomerase) (Dihydrotestosterone oxidoreductase) (EC 1.1.1.210) (Steroid Delta-isomerase) (EC 5.3.3.1) (Trophoblast antigen FDO161G)	5	UniProt NCBI
HSD3B2	3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 2 (3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type II) (3-beta-HSD II) (3-beta-HSD adrenal and gonadal type) [Includes: 3-beta-hydroxy-Delta(5)-steroid dehydrogenase (EC 1.1.1.145) (3-beta-hydroxy-5-ene steroid dehydrogenase) (Progesterone reductase); Steroid Delta-isomerase (EC 5.3.3.1) (Delta-5-3-ketosteroid isomerase)]	5	UniProt NCBI
TMEM38A	Trimeric intracellular cation channel type A (TRIC-A) (TRICA) (Transmembrane protein 38A)	4	UniProt NCBI

Showing 1 to 3 of 3 entries

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Term ID	Corrected Pval	Fraction Complex Coverage	Proteins	Term Name
WP:WP5277	0.0310970405539	0.5	HSD3B2	Steroid hormone precursor biosynthesis
WP:WP4873	0.0373151717536	0.5	HSD3B2	Peroxiredoxin 2 induced ovarian failure
WP:WP496	0.0435328773163	0.5	HSD3B2	Steroid biosynthesis
WP:WP4524	0.049750157242	0.5	HSD3B2	Alternative pathway of fetal androgen synthesis
WP:WP5320	0.049750157242	0.5	HSD3B2	Male steroid hormones in cardiomyocyte energy metabolism
HP:0031078	0.0499436884913	0.5	HSD3B2	Impaired cortisol response to corticotropin releasing hormone stimulation test
HP:0033809	0.0499436884913	0.5	HSD3B2	Increased circulating 17 hydroxypregnenolone concentration

Showing 1 to 7 of 7 entries

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Protein 1	Protein 2	Score	ProteomeHD	Interface Overlap	Evidence
TMEM38A	HSD3B2	0.997			bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM
HSD3B1	HSD3B2	0.994		structurally_consistent (dimer)	bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM
TMEM38A	HSD3B1	0.572			bioplex_WMM bioplex3_WMM WMM_only

Showing 1 to 3 of 3 entries

Related Complexes

Genename	Complexes
HSD3B1	huMAP3_01457.1 huMAP3_02933.1 huMAP3_06693.1 huMAP3_08909.1
TMEM38A	huMAP3_00883.1 huMAP3_02933.1 huMAP3_03831.1 huMAP3_06693.1 huMAP3_11081.1 huMAP3_12635.1 huMAP3_14983.1 huMAP3_15318.1
HSD3B2	huMAP3_01457.1 huMAP3_02933.1 huMAP3_06693.1 huMAP3_08909.1