hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_02943.1
Complex Portal: CPX-23175
Confidence: Extremely High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| PDZK1 | Na(+)/H(+) exchange regulatory cofactor NHE-RF3 (NHERF-3) (CFTR-associated protein of 70 kDa) (Na(+)/H(+) exchanger regulatory factor 3) (Na/Pi cotransporter C-terminal-associated protein 1) (NaPi-Cap1) (PDZ domain-containing protein 1) (Sodium-hydrogen exchanger regulatory factor 3) | 5 | UniProt NCBI |
| SH2D5 | SH2 domain-containing protein 5 | 3 | UniProt NCBI |
| SLC19A3 | Thiamine transporter 2 (ThTr-2) (ThTr2) (Solute carrier family 19 member 3) | 5 | UniProt NCBI |
| ASNSD1 | Asparagine synthetase domain-containing protein 1 (HCV NS3-transactivated protein 1) | 3 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:6793 | 0.049938562206 | 0.25 | PDZK1 | PDZK1-NHERF1-EZR complex |
| CORUM:7042 | 0.049938562206 | 0.25 | PDZK1 | PDZK1-PLCB3- SSTR2 complex |
| CORUM:7043 | 0.049938562206 | 0.25 | PDZK1 | PDZK1-PLCB3- SSTR3 complex |
| CORUM:7044 | 0.049938562206 | 0.25 | PDZK1 | PDZK1-PLCB3- SSTR4 complex |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| PDZK1 | SH2D5 | 0.997 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | ||
| PDZK1 | SLC19A3 | 0.993 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | ||
| PDZK1 | ASNSD1 | 0.992 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | ||
| SH2D5 | SLC19A3 | 0.572 | bioplex_WMM bioplex3_WMM WMM_only | ||
| SH2D5 | ASNSD1 | 0.333 | bioplex_WMM bioplex3_WMM WMM_only | ||
| SLC19A3 | ASNSD1 | 0.333 | bioplex_WMM bioplex3_WMM WMM_only |
Related Complexes