hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_02957.1
Complex Portal: CPX-20716
Confidence: Extremely High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| PRTFDC1 | Phosphoribosyltransferase domain-containing protein 1 | 5 | UniProt NCBI |
| CLDN3 | Claudin-3 (Clostridium perfringens enterotoxin receptor 2) (CPE-R 2) (CPE-receptor 2) (Rat ventral prostate.1 protein homolog) (hRVP1) | 5 | UniProt NCBI |
| HPRT1 | Hypoxanthine-guanine phosphoribosyltransferase (HGPRT) (HGPRTase) (EC 2.4.2.8) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-9734281 | 0.0498224659464 | 0.333333333333 | HPRT1 | Defective HPRT1 disrupts guanine and hypoxanthine salvage |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| PRTFDC1 | HPRT1 | 0.984 | 0.124 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | |
| CLDN3 | HPRT1 | 0.959 | 0.092 | bioplex3_HEK293 bioplex3_WMM bioplex3_HCT116 WMM_only |
Related Complexes
| Genename | Complexes |
|---|---|
| PRTFDC1 | huMAP3_02957.1 huMAP3_04249.1 |
| CLDN3 | huMAP3_02957.1 huMAP3_06771.1 huMAP3_06809.1 |
| HPRT1 | huMAP3_02957.1 huMAP3_04249.1 huMAP3_06771.1 |