hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_02959.1
Confidence: Extremely High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| STK38 | Serine/threonine-protein kinase 38 (EC 2.7.11.1) (NDR1 protein kinase) (Nuclear Dbf2-related kinase 1) | 5 | UniProt NCBI |
| MOB1B | MOB kinase activator 1B (Mob1 homolog 1A) (Mob1A) (Mob1B) (Mps one binder kinase activator-like 1A) | 5 | UniProt NCBI |
| MOB1A | MOB kinase activator 1A (Mob1 alpha) (Mob1A) (Mob1 homolog 1B) (Mps one binder kinase activator-like 1B) | 5 | UniProt NCBI |
| STK38L | Serine/threonine-protein kinase 38-like (EC 2.7.11.1) (NDR2 protein kinase) (Nuclear Dbf2-related kinase 2) | 5 | UniProt NCBI |
| MOB2 | MOB kinase activator 2 (HCCA2) (Mob2 homolog) (Mps one binder kinase activator-like 2) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| KEGG:04392 | 0.00147248543337 | 0.4 | MOB1A MOB1B | Hippo signaling pathway - multiple species |
| WP:WP4542 | 0.00237924603132 | 0.4 | MOB1A STK38L | Leukocyte intrinsic Hippo pathway functions |
| REAC:R-HSA-2028269 | 0.00259338296865 | 0.4 | MOB1A MOB1B | Signaling by Hippo |
| WP:WP5087 | 0.0098916730515 | 0.6 | MOB1A MOB1B STK38L | Pleural mesothelioma |
| GO:0006468 | 0.0389285508109 | 1.0 | STK38 STK38L MOB1B MOB2 MOB1A | protein phosphorylation |
| KEGG:04390 | 0.0471742362289 | 0.4 | MOB1A MOB1B | Hippo signaling pathway |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| STK38L | MOB2 | 1.0 | 0.096 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 boldt_WMM |
| STK38L | MOB1B | 0.999 | 0.28 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 |
| STK38 | MOB2 | 0.999 | 0.304 | bioplex3_HEK293 bioplex3_WMM youn_WMM bioplex3_HCT116 gupta_WMM fraction |
| STK38L | MOB1A | 0.999 | 0.16 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 |
| MOB1A | MOB1B | 0.99 | 0.672 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM |
| STK38 | MOB1B | 0.97 | 0.124 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM |
| STK38L | STK38 | 0.966 | 0.066 | bioplex3_HEK293 bioplex_WMM bioplex3_WMM gupta_WMM WMM_only |
| MOB2 | MOB1A | 0.868 | 0.056 | bioplex_WMM bioplex3_WMM WMM_only |
| STK38 | MOB1A | 0.333 | 0.1 | bioplex_WMM bioplex3_WMM WMM_only |
| MOB2 | MOB1B | 0.197 | 0.096 | bioplex_WMM bioplex3_WMM WMM_only |
Related Complexes