hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_02965.1
Confidence: Extremely High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| ABCE1 | ATP-binding cassette sub-family E member 1 (EC 3.6.5.-) (2'-5'-oligoadenylate-binding protein) (HuHP68) (RNase L inhibitor) (Ribonuclease 4 inhibitor) (RNS4I) | 5 | UniProt NCBI |
| PPT1 | Palmitoyl-protein thioesterase 1 (PPT-1) (EC 3.1.2.22) (Palmitoyl-protein hydrolase 1) | 5 | UniProt NCBI |
| B3GALT2 | Beta-1,3-galactosyltransferase 2 (Beta-1,3-GalTase 2) (Beta3Gal-T2) (Beta3GalT2) (EC 2.4.1.86) (UDP-galactose:2-acetamido-2-deoxy-D-glucose 3beta-galactosyltransferase 2) | 5 | UniProt NCBI |
| NEU1 | Sialidase-1 (EC 3.2.1.18) (Acetylneuraminyl hydrolase) (G9 sialidase) (Lysosomal sialidase) (N-acetyl-alpha-neuraminidase 1) | 5 | UniProt NCBI |
| LGMN | Legumain (EC 3.4.22.34) (Asparaginyl endopeptidase) (AEP) (Protease, cysteine 1) | 5 | UniProt NCBI |
| DSC2 | Desmocollin-2 (Cadherin family member 2) (Desmocollin-3) (Desmosomal glycoprotein II) (Desmosomal glycoprotein III) | 5 | UniProt NCBI |
| IGF2R | Cation-independent mannose-6-phosphate receptor (CI Man-6-P receptor) (CI-MPR) (M6PR) (300 kDa mannose 6-phosphate receptor) (MPR 300) (Insulin-like growth factor 2 receptor) (Insulin-like growth factor II receptor) (IGF-II receptor) (M6P/IGF2 receptor) (M6P/IGF2R) (CD antigen CD222) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| KEGG:04142 | 0.000591179114185 | 0.5 | PPT1 LGMN NEU1 | Lysosome |
| HP:0001922 | 0.00302198579101 | 0.333333333333 | PPT1 NEU1 | Vacuolated lymphocytes |
| CORUM:1379 | 0.0499436884912 | 0.166666666667 | NEU1 | GALNS-lysosomal hydrolase 1.27 MDa complex |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| ABCE1 | IGF2R | 0.993 | 0.108 | hein_WMM bioplex3_HEK293 bioplex_WMM bioplex3_WMM boldt youn_WMM gupta_WMM boldt_WMM WMM_only |
| PPT1 | IGF2R | 0.985 | 0.146 | bioplex3_HEK293 bioplex_WMM bioplex3_WMM bioplex3_HCT116 WMM_only |
| B3GALT2 | IGF2R | 0.985 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | |
| LGMN | IGF2R | 0.98 | 0.104 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 |
| PPT1 | LGMN | 0.978 | 0.11 | bioplex3_HEK293 bioplex_WMM bioplex3_WMM bioplex3_HCT116 WMM_only |
| DSC2 | IGF2R | 0.971 | 0.158 | bioplex_WMM bioplex3_WMM youn_WMM gupta_WMM WMM_only |
| NEU1 | IGF2R | 0.968 | 0.076 | bioplex3_HEK293 bioplex_WMM bioplex3_WMM WMM_only |
| ABCE1 | B3GALT2 | 0.913 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | |
| PPT1 | NEU1 | 0.844 | 0.094 | bioplex_WMM bioplex3_WMM WMM_only treiber_WMM |
| NEU1 | LGMN | 0.631 | 0.084 | bioplex_WMM bioplex3_WMM WMM_only |
| DSC2 | LGMN | 0.593 | 0.128 | bioplex_WMM bioplex3_WMM WMM_only |
| PPT1 | DSC2 | 0.166 | 0.086 | bioplex3_HEK293 bioplex_WMM bioplex3_WMM WMM_only |
| PPT1 | ABCE1 | 0.072 | 0.078 | bioplex3_HEK293 bioplex_WMM bioplex3_WMM bioplex3_HCT116 WMM_only |
| DSC2 | B3GALT2 | 0.047 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | |
| DSC2 | NEU1 | 0.024 | 0.052 | bioplex_WMM bioplex3_WMM WMM_only |
| PPT1 | B3GALT2 | 0.018 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | |
| ABCE1 | LGMN | 0.017 | 0.056 | bioplex_WMM bioplex3_WMM bioplex3_HCT116 WMM_only |
| DSC2 | ABCE1 | 0.008 | 0.118 | bioplex_WMM bioplex3_WMM youn_WMM gupta_WMM WMM_only |
| B3GALT2 | LGMN | 0.006 | bioplex3_HEK293 bioplex () | |
| ABCE1 | NEU1 | 0.004 | 0.04 | bioplex_WMM bioplex3_WMM WMM_only |
Related Complexes