hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_02976.1
Complex Portal: CPX-11546
Confidence: Extremely High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| CHEK1 | Serine/threonine-protein kinase Chk1 (EC 2.7.11.1) (CHK1 checkpoint homolog) (Cell cycle checkpoint kinase) (Checkpoint kinase-1) | 5 | UniProt NCBI |
| HVCN1 | Voltage-gated hydrogen channel 1 (Hydrogen voltage-gated channel 1) (HV1) (Voltage sensor domain-only protein) | 5 | UniProt NCBI |
| NAT9 | Alpha/beta-tubulin-N-acetyltransferase 9 (EC 2.3.1.308) (Embryo brain-specific protein) | 3 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:2171 | 0.0499402709677 | 0.333333333333 | CHEK1 | Ubiquitin E3 ligase (CHEK1, CUL4A) |
| CORUM:2714 | 0.0499402709677 | 0.333333333333 | CHEK1 | Ubiquitin E3 ligase (CHEK1, CUL1) |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| CHEK1 | HVCN1 | 0.991 | 0.042 | bioplex3_HEK293 bioplex3_WMM bioplex3_HCT116 WMM_only | |
| CHEK1 | NAT9 | 0.967 | 0.066 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM |
Related Complexes
| Genename | Complexes |
|---|---|
| CHEK1 | huMAP3_02976.1 huMAP3_03254.1 huMAP3_08430.1 huMAP3_09277.1 huMAP3_09345.1 huMAP3_12506.1 huMAP3_14678.1 |
| HVCN1 | huMAP3_02976.1 |
| NAT9 | huMAP3_02976.1 huMAP3_13844.1 |