hu.MAP 3.0: Complex View

Human Protein Complex Map

Complex: huMAP3_02984.1

Confidence: Extremely High

Genename	Protein Name	Uniprot Annotation Score	Links
IER5L	Immediate early response gene 5-like protein	2	UniProt NCBI
CDCA4	Cell division cycle-associated protein 4 (Hematopoietic progenitor protein)	5	UniProt NCBI
RAB11FIP5	Rab11 family-interacting protein 5 (Rab11-FIP5) (Gamma-SNAP-associated factor 1) (Gaf-1) (Phosphoprotein pp75) (Rab11-interacting protein Rip11)	5	UniProt NCBI
FBXL16	F-box/LRR-repeat protein 16 (F-box and leucine-rich repeat protein 16)	4	UniProt NCBI
IGFBP5	Insulin-like growth factor-binding protein 5 (IBP-5) (IGF-binding protein 5) (IGFBP-5)	5	UniProt NCBI
FOXC2	Forkhead box protein C2 (Forkhead-related protein FKHL14) (Mesenchyme fork head protein 1) (MFH-1 protein) (Transcription factor FKH-14)	5	UniProt NCBI
PPP2R2B	Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B beta isoform (PP2A subunit B isoform B55-beta) (PP2A subunit B isoform PR55-beta) (PP2A subunit B isoform R2-beta) (PP2A subunit B isoform beta)	5	UniProt NCBI
PPP2R2D	Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B delta isoform (PP2A subunit B isoform B55-delta) (PP2A subunit B isoform PR55-delta) (PP2A subunit B isoform R2-delta) (PP2A subunit B isoform delta)	4	UniProt NCBI
FOXS1	Forkhead box protein S1 (Forkhead-like 18 protein) (Forkhead-related transcription factor 10) (FREAC-10)	4	UniProt NCBI
SERTAD1	SERTA domain-containing protein 1 (CDK4-binding protein p34SEI1) (SEI-1) (p34(SEI-1)) (Transcriptional regulator interacting with the PHD-bromodomain 1) (TRIP-Br1)	5	UniProt NCBI
PPP2R2A	Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B alpha isoform (PP2A subunit B isoform B55-alpha) (PP2A subunit B isoform PR55-alpha) (PP2A subunit B isoform R2-alpha) (PP2A subunit B isoform alpha)	5	UniProt NCBI

Enrichments

Term ID	Corrected Pval	Fraction Complex Coverage	Proteins	Term Name
KEGG:05142	0.00171316596072	0.272727272727	PPP2R2B PPP2R2D PPP2R2A	Chagas disease
KEGG:03015	0.00189424703244	0.272727272727	PPP2R2B PPP2R2D PPP2R2A	mRNA surveillance pathway
KEGG:04071	0.00274394643647	0.272727272727	PPP2R2B PPP2R2D PPP2R2A	Sphingolipid signaling pathway
KEGG:04660	0.00274394643647	0.272727272727	PPP2R2B PPP2R2D PPP2R2A	T cell receptor signaling pathway
KEGG:04728	0.00324920943997	0.272727272727	PPP2R2B PPP2R2D PPP2R2A	Dopaminergic synapse
KEGG:04152	0.00361782510403	0.272727272727	PPP2R2B PPP2R2D PPP2R2A	AMPK signaling pathway
KEGG:04261	0.00422055419317	0.272727272727	PPP2R2B PPP2R2D PPP2R2A	Adrenergic signaling in cardiomyocytes
KEGG:05160	0.00561579887786	0.272727272727	PPP2R2B PPP2R2D PPP2R2A	Hepatitis C
KEGG:04530	0.00669560177237	0.272727272727	PPP2R2B PPP2R2D PPP2R2A	Tight junction
KEGG:04390	0.00774471138932	0.272727272727	PPP2R2B PPP2R2D PPP2R2A	Hippo signaling pathway
GO:0000159	0.012862104388	0.272727272727	PPP2R2B PPP2R2D PPP2R2A	protein phosphatase type 2A complex
WP:WP500	0.0352932028921	0.181818181818	PPP2R2B PPP2R2A	Glycogen synthesis and degradation
CORUM:5107	0.049976851631	0.0909090909091	SERTAD1	p34(SEI-1)-CDK4-CyclinD2 complex

Edges

Protein 1	Protein 2	Score	ProteomeHD	Evidence
PPP2R2D	PPP2R2A	1.0	0.754	hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM boldt hein () bioplex3_HCT116 gupta_WMM boldt_WMM
CDCA4	PPP2R2A	0.999	0.068	hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM hein () bioplex3_HCT116
FBXL16	IGFBP5	0.998		bioplex3_WMM bioplex3_HCT116 WMM_only
CDCA4	PPP2R2B	0.997	0.0600670391061	hein_WMM bioplex3_HEK293 bioplex_WMM bioplex3_WMM bioplex3_HCT116 WMM_only
RAB11FIP5	PPP2R2D	0.996	0.012	hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116
CDCA4	PPP2R2D	0.995	0.056	hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116
RAB11FIP5	FOXC2	0.995	0.072	hein_WMM bioplex_WMM bioplex3_WMM WMM_only
FOXC2	PPP2R2A	0.994	0.18	hein_WMM bioplex_WMM bioplex3_WMM hein ()
FBXL16	PPP2R2B	0.994		hein_WMM bioplex3_WMM bioplex3_HCT116 WMM_only
PPP2R2D	FOXS1	0.994		bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116
CDCA4	FOXC2	0.993	0.066	hein_WMM bioplex_WMM bioplex3_WMM WMM_only
FOXC2	PPP2R2D	0.992	0.084	hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM
FBXL16	PPP2R2D	0.987		hein_WMM bioplex3_WMM hein ()
FOXS1	PPP2R2A	0.987		bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116
RAB11FIP5	PPP2R2A	0.984	0.15	hein_WMM bioplex3_HEK293 bioplex_WMM bioplex3_WMM youn_WMM hein () bioplex3_HCT116 gupta_WMM
IGFBP5	PPP2R2A	0.982	0.07	bioplex3_HEK293 bioplex3_WMM bioplex3_HCT116 WMM_only
IER5L	PPP2R2B	0.982		bioplex3_WMM bioplex3_HCT116 WMM_only
IER5L	PPP2R2D	0.98		bioplex3_WMM bioplex3_HCT116 WMM_only
PPP2R2B	PPP2R2D	0.976	0.922	hein_WMM bioplex3_WMM bioplex3_HCT116 gupta_WMM WMM_only
PPP2R2D	SERTAD1	0.972		bioplex3_HEK293 bioplex3_WMM bioplex3_HCT116 WMM_only
RAB11FIP5	PPP2R2B	0.961	0.06	hein_WMM bioplex3_HEK293 bioplex3_WMM gupta_WMM WMM_only
PPP2R2B	PPP2R2A	0.961	0.904	hein_WMM bioplex3_HEK293 bioplex_WMM bioplex3_WMM gupta_WMM WMM_only
FBXL16	CDCA4	0.959		hein_WMM bioplex3_WMM WMM_only
SERTAD1	PPP2R2A	0.957		bioplex3_HEK293 bioplex3_WMM bioplex3_HCT116 WMM_only
CDCA4	RAB11FIP5	0.956	0.04	hein_WMM bioplex_WMM bioplex3_WMM WMM_only
IGFBP5	PPP2R2D	0.951	0.034	bioplex3_HEK293 bioplex3_WMM bioplex3_HCT116 WMM_only
FBXL16	PPP2R2A	0.927		hein_WMM bioplex3_WMM hein () bioplex3_HCT116
FOXC2	PPP2R2B	0.895	0.086	hein_WMM bioplex3_WMM WMM_only
FBXL16	RAB11FIP5	0.818		hein_WMM bioplex3_WMM WMM_only
FBXL16	FOXC2	0.796		hein_WMM WMM_only
FBXL16	IER5L	0.688		bioplex3_WMM WMM_only
IER5L	PPP2R2A	0.587		bioplex3_WMM WMM_only
IER5L	CDCA4	0.455		bioplex3_WMM WMM_only
IER5L	RAB11FIP5	0.32		bioplex3_WMM WMM_only
IER5L	FOXC2	0.214		bioplex3_WMM WMM_only

Related Complexes

Genename	Complexes
IER5L	huMAP3_02984.1 huMAP3_04822.1 huMAP3_06067.1 huMAP3_06552.1 huMAP3_09709.1 huMAP3_10333.1 huMAP3_10604.1 huMAP3_11951.1 huMAP3_13510.1 huMAP3_13681.1 huMAP3_14060.1
CDCA4	huMAP3_02984.1 huMAP3_06552.1 huMAP3_09709.1 huMAP3_10333.1 huMAP3_13510.1 huMAP3_13681.1
RAB11FIP5	huMAP3_02984.1 huMAP3_06552.1 huMAP3_09709.1 huMAP3_10333.1 huMAP3_13510.1
FBXL16	huMAP3_00161.1 huMAP3_00839.1 huMAP3_02984.1 huMAP3_05528.1 huMAP3_06552.1 huMAP3_09623.1 huMAP3_09719.1 huMAP3_09743.1 huMAP3_10333.1 huMAP3_13510.1 huMAP3_14622.1
IGFBP5	huMAP3_02984.1 huMAP3_05452.1 huMAP3_06552.1 huMAP3_08168.1 huMAP3_09743.1 huMAP3_10333.1
FOXC2	huMAP3_02984.1 huMAP3_06695.1 huMAP3_07998.1 huMAP3_09709.1 huMAP3_10333.1 huMAP3_13510.1
PPP2R2B	huMAP3_02984.1 huMAP3_04822.1 huMAP3_06067.1 huMAP3_06552.1 huMAP3_09709.1 huMAP3_10333.1 huMAP3_10604.1 huMAP3_13510.1 huMAP3_13681.1
PPP2R2D	huMAP3_02984.1 huMAP3_06552.1 huMAP3_09743.1 huMAP3_10333.1 huMAP3_11665.1 huMAP3_13510.1
FOXS1	huMAP3_02984.1 huMAP3_06552.1 huMAP3_09743.1 huMAP3_10333.1 huMAP3_13510.1 huMAP3_14374.1
SERTAD1	huMAP3_02984.1 huMAP3_06552.1 huMAP3_09743.1 huMAP3_10333.1 huMAP3_11509.1 huMAP3_12758.1 huMAP3_13510.1 huMAP3_13517.1 huMAP3_14224.1
PPP2R2A	huMAP3_02984.1 huMAP3_06552.1 huMAP3_09743.1 huMAP3_10333.1 huMAP3_13510.1

hu.MAP 3.0: Complex View

Search for a protein

Complex: huMAP3_02984.1