hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_02989.1
Confidence: Extremely High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| MCM8 | DNA helicase MCM8 (EC 3.6.4.12) (Minichromosome maintenance 8) | 5 | UniProt NCBI |
| MCM9 | DNA helicase MCM9 (hMCM9) (EC 3.6.4.12) (Mini-chromosome maintenance deficient domain-containing protein 1) (Minichromosome maintenance 9) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| GO:0032406 | 0.000468200720083 | 1.0 | MCM8 MCM9 | MutLbeta complex binding |
| GO:0032408 | 0.000468200720083 | 1.0 | MCM8 MCM9 | MutSbeta complex binding |
| GO:0097362 | 0.000468200720083 | 1.0 | MCM8 MCM9 | MCM8-MCM9 complex |
| GO:0036298 | 0.000468200720083 | 1.0 | MCM8 MCM9 | recombinational interstrand cross-link repair |
| GO:0070716 | 0.000468200720083 | 1.0 | MCM8 MCM9 | mismatch repair involved in maintenance of fidelity involved in DNA-dependent DNA replication |
| HP:0008232 | 0.00138751454273 | 1.0 | MCM8 MCM9 | Elevated circulating follicle stimulating hormone level |
| WP:WP5316 | 0.00351405922273 | 1.0 | MCM8 MCM9 | Primary ovarian insufficiency |
| HP:0030346 | 0.00489047613459 | 1.0 | MCM8 MCM9 | Abnormal circulating follicle-stimulating hormone concentration |
| HP:0000837 | 0.00526298619656 | 1.0 | MCM8 MCM9 | Increased circulating gonadotropin level |
| WP:WP4352 | 0.00925164622885 | 1.0 | MCM8 MCM9 | Ciliary landscape |
| GO:0032407 | 0.00983221512175 | 1.0 | MCM8 MCM9 | MutSalpha complex binding |
| HP:0030338 | 0.011629832485 | 1.0 | MCM8 MCM9 | Abnormal circulating gonadotropin concentration |
| HP:0010514 | 0.0127849554294 | 1.0 | MCM8 MCM9 | Hyperpituitarism |
| HP:0000786 | 0.0146201655512 | 1.0 | MCM8 MCM9 | Primary amenorrhea |
| GO:0032404 | 0.0257510396046 | 1.0 | MCM8 MCM9 | mismatch repair complex binding |
| GO:0042555 | 0.0257510396046 | 1.0 | MCM8 MCM9 | MCM complex |
| HP:0000141 | 0.0371758206793 | 1.0 | MCM8 MCM9 | Amenorrhea |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| MCM9 | MCM8 | 0.999 | 0.058 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 |
Related Complexes
| Genename | Complexes |
|---|---|
| MCM8 | huMAP3_02989.1 huMAP3_11875.1 huMAP3_13174.1 huMAP3_13604.1 huMAP3_14877.1 |
| MCM9 | huMAP3_02489.1 huMAP3_02989.1 huMAP3_10576.1 huMAP3_13174.1 huMAP3_14877.1 |