hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_03028.1
Confidence: Extremely High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| INTS15 | Integrator complex subunit 15 | 3 | UniProt NCBI |
| INTS13 | Integrator complex subunit 13 (Cell cycle regulator Mat89Bb homolog) (Germ cell tumor 1) (Protein asunder homolog) (Sarcoma antigen NY-SAR-95) | 5 | UniProt NCBI |
| FEM1A | Protein fem-1 homolog A (FEM1a) (FEM1-alpha) (Prostaglandin E receptor 4-associated protein) | 5 | UniProt NCBI |
| INTS10 | Integrator complex subunit 10 (Int10) | 4 | UniProt NCBI |
| DHRS3 | Short-chain dehydrogenase/reductase 3 (EC 1.1.1.300) (DD83.1) (Retinal short-chain dehydrogenase/reductase 1) (retSDR1) (Retinol dehydrogenase 17) (Short chain dehydrogenase/reductase family 16C member 1) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| GO:0032039 | 0.000929874009882 | 0.6 | INTS15 INTS10 INTS13 | integrator complex |
| WP:WP5345 | 0.0132783799217 | 0.4 | INTS13 INTS10 | 1p36 copy number variation syndrome |
| REAC:R-HSA-6807505 | 0.0384836492499 | 0.4 | INTS13 INTS10 | RNA polymerase II transcribes snRNA genes |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| INTS13 | INTS10 | 0.997 | 0.184 | hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM |
| INTS15 | FEM1A | 0.988 | 0.098 | bioplex3_HEK293 bioplex3_WMM WMM_only |
| FEM1A | DHRS3 | 0.987 | 0.13 | bioplex3_HEK293 bioplex3_WMM bioplex3_HCT116 WMM_only |
| INTS10 | FEM1A | 0.974 | 0.126 | bioplex3_HEK293 bioplex3_WMM WMM_only |
| INTS13 | FEM1A | 0.963 | 0.1 | bioplex3_HEK293 bioplex3_WMM WMM_only |
| INTS13 | INTS15 | 0.673 | 0.19 | bioplex3_WMM Malo fraction |
| INTS10 | INTS15 | 0.415 | 0.254 | bioplex3_WMM WMM_only |
| INTS15 | DHRS3 | 0.25 | 0.078 | bioplex3_WMM WMM_only |
| INTS10 | DHRS3 | 0.25 | 0.034 | bioplex3_WMM WMM_only |
| INTS13 | DHRS3 | 0.078 | 0.026 | bioplex3_WMM WMM_only |
Related Complexes