hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_03030.1
Confidence: Extremely High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| IL2 | Interleukin-2 (IL-2) (T-cell growth factor) (TCGF) (Aldesleukin) | 5 | UniProt NCBI |
| IL17A | Interleukin-17A (IL-17) (IL-17A) (Cytotoxic T-lymphocyte-associated antigen 8) (CTLA-8) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| WP:WP5285 | 0.000138332030934 | 1.0 | IL2 IL17A | Immune infiltration in pancreatic cancer |
| KEGG:05321 | 0.000146800434109 | 1.0 | IL2 IL17A | Inflammatory bowel disease |
| KEGG:04659 | 0.000651091626366 | 1.0 | IL2 IL17A | Th17 cell differentiation |
| WP:WP5130 | 0.000679316681139 | 1.0 | IL2 IL17A | Th17 cell differentiation pathway |
| WP:WP2328 | 0.000941083447368 | 1.0 | IL2 IL17A | Allograft rejection |
| WP:WP5098 | 0.00114964558631 | 1.0 | IL2 IL17A | T cell activation SARS CoV 2 |
| WP:WP5095 | 0.00148377064565 | 1.0 | IL2 IL17A | Overview of proinflammatory and profibrotic mediators |
| KEGG:04060 | 0.0031385705215 | 1.0 | IL2 IL17A | Cytokine-cytokine receptor interaction |
| WP:WP5256 | 0.0248784837172 | 0.5 | IL17A | COVID 19 and endothelial cell senescence |
| WP:WP4484 | 0.049750157242 | 0.5 | IL2 | Control of immune tolerance by vasoactive intestinal peptide |
| CORUM:1707 | 0.0499419797295 | 0.5 | IL2 | IL2-IL2RA-IL2RB complex |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| IL2 | IL17A | 1.0 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 |
Related Complexes
| Genename | Complexes |
|---|---|
| IL2 | huMAP3_03030.1 huMAP3_09900.1 huMAP3_15154.1 |
| IL17A | huMAP3_03030.1 huMAP3_09900.1 huMAP3_15154.1 |