hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_03033.1
Confidence: Extremely High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| SFTPA2 | Pulmonary surfactant-associated protein A2 (PSP-A) (PSPA) (SP-A) (SP-A2) (35 kDa pulmonary surfactant-associated protein) (Alveolar proteinosis protein) (Collectin-5) | 5 | UniProt NCBI |
| LIMK2 | LIM domain kinase 2 (LIMK-2) (EC 2.7.11.1) | 5 | UniProt NCBI |
| NKIRAS1 | NF-kappa-B inhibitor-interacting Ras-like protein 1 (I-kappa-B-interacting Ras-like protein 1) (Kappa B-Ras protein 1) (KappaB-Ras1) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-181438 | 0.0316091445651 | 0.666666666667 | SFTPA2 NKIRAS1 | Toll Like Receptor 2 (TLR2) Cascade |
| REAC:R-HSA-168179 | 0.0316091445651 | 0.666666666667 | SFTPA2 NKIRAS1 | Toll Like Receptor TLR1:TLR2 Cascade |
| REAC:R-HSA-5687868 | 0.0498224659464 | 0.333333333333 | SFTPA2 | Defective SFTPA2 causes IPF |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| SFTPA2 | LIMK2 | 0.999 | bioplex3_HEK293 bioplex3_WMM bioplex3_HCT116 WMM_only | |
| SFTPA2 | NKIRAS1 | 0.998 | bioplex3_WMM bioplex3_HCT116 WMM_only | |
| LIMK2 | NKIRAS1 | 0.343 | 0.07 | bioplex3_WMM WMM_only |
Related Complexes